Gene Expression Data Analysis

Pankaj Barah is an Assistant professor in Molecular Biology and Biotechnology at Tezpur University. He has received his M.Sc. degree in Bioinformatics (2006) from University of Madras in India and PhD in Computational Systems Biology (2013) from the Norwegian University of Science and Technology (NTNU), Trondheim, Norway. He has worked as Bioinformatics scientist in the division of Theoretical Bioinformatics at German Cancer Research Center (DKFZ) in Heidelberg, Germany during 2015-2017. His research areas include- computational systems biology, bioinformatics, evolutionary systems biology, Next Generation Sequencing (NGS), Big data analytics and biological networks. He has authored 20 research articles, edited two books and written 5 book chapters. He is recipient of Ramalingaswami Re-entry Fellowship from the Department of Biotechnology, Government of India. Dr. Barah is currently a member of the Indian National Young Academy of Sciences. Dhruba Kumar Bhattacharyya is a professor in Computer Science and Engineering at Tezpur University. He teaches machine learning, network security, cryptography and computational biology in UG, PG and PhD classes at Tezpur University. Professor Bhattacharyya's research areas include machine learning, network security, and bioinformatics. He has published more than 280 research articles in leading international journals and peer-reviewed conference proceedings. Dr. Bhattacharyya has authored 5 technical reference books and edited 9 technical volumes. Under his guidance, twenty students have successfully completed Ph.D. in the areas of machine learning, bioinformatics and network security. He is PI of several major research grants, including the Centre of Excellence of Ministry of HRD of Government of India under FAST instituted at Tezpur University. Professor Bhattacharyya is a Fellow of IETE and IE, India. He is also a Senior Member of IEEE. More details about Dr Bhattacharyya can be found at http://agnigarh.tezu.ernet.in/_dkb/index.html. Jugal Kumar Kalita teaches computer science at the University of Colorado, Colorado Springs. He received M.S. and Ph.D. degrees in computer and information science from the University of Pennsylvania in Philadelphia in 1988 and 1990, respectively. Prior to that he had received an M.Sc. from the University of Saskatchewan in Saskatoon, Canada in 1984 and a B.Tech. from the Indian Institute of Technology, Kharagpur in 1982. His expertise is in the areas of artificial intelligence and machine learning, and the application of techniques in machine learning to network security, natural language processing and bioinformatics. He has published 130 papers in journals and refereed conferences. He is the author of a book on Perl titled "On Perl: Perl for Students and Professionals". He is also a coauthor of a book titled "Network Anomaly Detection: A Machine Learning Perspective" with Dr Dhruba K Bhattacharyya. He received the Chancellor's Award at the University of Colorado, Colorado Springs, in 2011, in recognition of lifelong excellence in teaching, research and service. More details about Dr. Kalita can be found at http://www.cs.uccs.edu/_kalita.

Preface. Acknowledgements. Abstract. Authors. Introduction. Information Flow in Biological Systems. Gene Expression Data Generation. Statistical Foundations and Machine Learning. Co-expression Analysis. Differential Expression Analysis. Tools and Systems. Concluding Remarks and Research Challenges. Index. Glossary.