Kidney Development, Disease, Repair and Regeneration -

Kidney Development, Disease, Repair and Regeneration (eBook)

Melissa Helen Little (Herausgeber)

eBook Download: PDF | EPUB
2015 | 1. Auflage
614 Seiten
Elsevier Science (Verlag)
978-0-12-800438-8 (ISBN)
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Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers across experimental nephrology and developmental biology will find this a key reference for learning how the underlying developmental mechanisms of the kidney will lead to greater advances in regenerative medicine within nephrology.


  • Offers researchers a single comprehensive resource written by leaders from both the developmental biology and the experimental nephrology communities
  • Focuses on understanding the molecular basis of organogenesis in the kidney as well as how this can be affected both genetically and environmentally
  • Explains the underlying developmental mechanisms which influence the kidney's inherent repair capacity
  • Demonstrates how a deeper understanding of mechanisms will lead to greater advances in regenerative medicine

Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers across experimental nephrology and developmental biology will find this a key reference for learning how the underlying developmental mechanisms of the kidney will lead to greater advances in regenerative medicine within nephrology. Offers researchers a single comprehensive resource written by leaders from both the developmental biology and the experimental nephrology communities Focuses on understanding the molecular basis of organogenesis in the kidney as well as how this can be affected both genetically and environmentally Explains the underlying developmental mechanisms which influence the kidney's inherent repair capacity Demonstrates how a deeper understanding of mechanisms will lead to greater advances in regenerative medicine

Contributors


Qais Al-Awqati,     Department of Medicine, Columbia University College of Physicians & Surgeons, New York, NY, USA

H.H. Arts,     Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboudumc, Nijmegen, The Netherlands

Anthony Atala,     Wake Forest School of Medicine, Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, USA

Felicity J. Barnes,     Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia

Ariela Benigni,     IRCCS — Istituto di Ricerche Farmacologiche “Mario Negri”, Centro Anna Maria Astori, Science & Technology Park Kilometro Rosso Bergamo, Italy

John F. Bertram,     Department of Anatomy and Developmental Biology, School of Biomedical Sciences, Monash University, Melbourne, VIC, Australia

M. Jane Black,     Department of Anatomy and Developmental Biology, Monash University, Melbourne, VIC, Australia

Joseph V. Bonventre

Renal Division and Biomedical Engineering Division, Brigham and Women’s Hospital, Department of Medicine, Harvard Medical School, Boston, MA, USA

Division of Health Sciences and Technology, Harvard-Massachusetts Institute of Technology, Cambridge, MA, USA

Harvard Stem Cell Institute, Cambridge, MA, USA

Deborah A. Buffington,     Innovative BioTherapies, Incorporated, Ann Arbor, MI, USA

Kevin T. Bush,     Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA

Qi Cao,     Centre for Transplant and Renal Research, Westmead Millennium Institute, University of Sydney at Westmead Hospital, Westmead, NSW, Australia

Thomas Carroll,     Departments of Molecular Biology and Internal Medicine (Nephrology), University of Texas Southwestern Medical Center, Dallas, TX, USA

Melanie Cosgrove,     Department of Experimental Medicine, McGill University, Montreal, QC, Canada

Frank Costantini,     Department of Genetics and Development, Columbia University, New York, NY, USA

Luise Cullen-McEwen,     Department of Anatomy and Developmental Biology, Monash University, Melbourne, VIC, Australia

Alan J. Davidson,     Department of Molecular Medicine & Pathology, School of Medical Sciences, Faculty of Medical Health Sciences, The University of Auckland, Auckland, New Zealand

Benjamin Dekel

Pediatric Stem Cell Research Institute, Edmond & Lili Safra Children’s Hospital, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

Division of Pediatric Nephrology, Edmond & Lili Safra Children’s Hospital, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

Rachel C. Dodd,     Department of Molecular Medicine & Pathology, School of Medical Sciences, Faculty of Medical Health Sciences, The University of Auckland, Auckland, New Zealand

Gregory R. Dressler,     Department of Pathology, University of Michigan, Ann Arbor, MI, USA

Jeremy S. Duffield

Research & Development, Biogen, Cambridge, MA, USA

Departments of Medicine & Pathology, University of Washington, Seattle, WA, USA

Klaudyna Dziedzic,     Pediatric Stem Cell Research Institute, Edmond & Lili Safra Children’s Hospital, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

David A. Ferenbach

Renal Division and Biomedical Engineering Division, Brigham and Women’s Hospital, Department of Medicine, Harvard Medical School, Boston, MA, USA

Centre for Inflammation Research, Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK

Julia B. Finkelstein,     Department of Urology, Columbia University College of Physicians and Surgeons, New York, NY, USA

Paul Goodyer

Department of Pediatrics, McGill University, Montreal, QC, Canada

Department of Human Genetics, McGill University, Montreal, QC, Canada

L.M. Guay-Woodford,     Center for Translational Science, Children’s National Health System, Washington, DC, USA

Marc R. Hammerman,     Renal Division, Departments of Medicine, and Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA

David C.H. Harris,     Sydney Medical School – Western Centre for Transplant and Renal Research, Westmead Millennium Institute, University of Sydney at Westmead Hospital, Westmead, NSW, Australia

Michael J. Hiatt,     Developmental Biology and Regenerative Medicine Program, The Saban Research Institute, Children’s Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA

Wendy E. Hoy,     Centre for Chronic Disease, University of Queensland, Brisbane, QLD, Australia

Michael D. Hughson,     Department of Pathology, University of Mississippi Medical Center, Jackson, MS, USA

Jennifer C. Huling

Wake Forest School of Medicine, Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, USA

School of Biomedical Engineering and Sciences, Virginia Tech-Wake Forest University, Winston-Salem, NC, USA

H. David Humes

Innovative BioTherapies, Incorporated, Ann Arbor, MI, USA

The University of Michigan, Ann Arbor, MI, USA

Benjamin D. Humphreys

Renal Division, Brigham and Women’s Hospital, Boston, MA, USA

Harvard Medical School, Boston, MA, USA

Harvard Stem Cell Institute, Cambridge, MA, USA

Roger Ilagan,     Division of Regenerative Medicine, United Therapeutics Corporation, Research Triangle Park, NC, USA

Nine V.A.M. Knoers,     Department of Medical Genetics, University Medical Centre Utrecht, Utrecht, The Netherlands

Raphael Kopan,     Division of Developmental Biology, Cincinnati Children’s Hospital, Cincinnati, OH, USA

Jordan A. Kreidberg,     Department of Medicine, Boston Children’s Hospital, and Department of Pediatrics, Harvard Medical School, Boston, MA, USA

Callie S. Kwartler,     Departments of Molecular Biology and Internal Medicine (Nephrology), University of Texas Southwestern Medical Center, Dallas, TX, USA

Laura Lasagni,     Excellence Centre for Research, Transfer and High Education for the Development of DE NOVO Therapies (DENOTHE), University of Florence, Florence, Italy

Elena Lazzeri,     Excellence Centre for Research, Transfer and High Education for the Development of DE NOVO Therapies (DENOTHE), University of Florence, Florence, Italy

Melissa H. Little,     The Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia

Weining Lu,     Department of Medicine, Boston University School of Medicine, Boston Medical Center, Boston, MA, USA

Daniela Macconi,     IRCCS — Istituto di Ricerche Farmacologiche “Mario Negri”, Centro Anna Maria Astori, Science & Technology Park Kilometro Rosso Bergamo, Italy

Douglas G. Matsell,     Child and Family Research Institute, British Columbia Children’s Hospital, University of British Columbia, Vancouver, BC, Canada

Andrew P. McMahon,     Department of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, WM Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA

Cathy Mendelsohn,     Departments of Urology, Genetics and Development and Pathology, Columbia University, New York, NY, USA

Marcus J. Moeller,     Department of Nephrology and Immunology, RWTH Aachen University, Aachen, Germany

Karen M. Moritz,     School of Biomedical Science, The University of Queensland, St Lucia, QLD, Australia

Sanjay K. Nigam

Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA

Department of Medicine, University of California, San Diego, La Jolla, CA, USA

Department of Cellular & Molecular Medicine, University of California, San Diego, La Jolla, CA, USA

Ryuichi Nishinakamura,     Department of Kidney Development, Institute of Molecular...

Erscheint lt. Verlag 6.8.2015
Sprache englisch
Themenwelt Medizinische Fachgebiete Innere Medizin Nephrologie
Medizin / Pharmazie Medizinische Fachgebiete Urologie
Studium 1. Studienabschnitt (Vorklinik) Physiologie
Naturwissenschaften Biologie Genetik / Molekularbiologie
Naturwissenschaften Biologie Humanbiologie
ISBN-10 0-12-800438-X / 012800438X
ISBN-13 978-0-12-800438-8 / 9780128004388
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