CPP, Cell-Penetrating Peptides - Ülo Langel

CPP, Cell-Penetrating Peptides

(Autor)

Buch | Softcover
470 Seiten
2020 | 1st ed. 2019
Springer Verlag, Singapore
978-981-13-8749-4 (ISBN)
139,09 inkl. MwSt
In this book, a summary and update of the most important areas of CPP research are presented, whilst raising relevant questions for further development.
In this book, a summary and update of the most important areas of CPP research are presented, whilst  raising relevant questions for further development. 

The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of CPPs, both in vitro and in vivo are discussed. Therapeutic potential of CPPs and commercial developments are discussed. 

The monograph is written for researchers and students in the field.

Classes and applications of CPP.- CPP functionalization.- Protein delivery and mimicry.- Targeting strategies.- Methods for detection and visualization of CPPs.- Methods for structural studies of CPPs.- Kinetics.- Toxicity and immune response.- Cell-translocation mechanisms of CPPs.- Clinical trials and commercialization using CPPs.- Therapeutic potential of CPPs.

Erscheinungsdatum
Zusatzinfo 17 Illustrations, color; 8 Illustrations, black and white; XII, 470 p. 25 illus., 17 illus. in color.
Verlagsort Singapore
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizin / Pharmazie Pharmazie
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Genetik / Molekularbiologie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Naturwissenschaften Chemie Organische Chemie
Schlagworte CPP processing • CPP uptake • Drug Delivery • Protein / peptide transduction domain • Trojan peptide
ISBN-10 981-13-8749-4 / 9811387494
ISBN-13 978-981-13-8749-4 / 9789811387494
Zustand Neuware
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