CPP, Cell-Penetrating Peptides - Ülo Langel

CPP, Cell-Penetrating Peptides

(Autor)

Buch | Hardcover
470 Seiten
2019 | 1st ed. 2019
Springer Verlag, Singapore
978-981-13-8746-3 (ISBN)
213,99 inkl. MwSt
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In this book, a summary and update of the most important areas of CPP research are presented, whilst raising relevant questions for further development.
In this book, a summary and update of the most important areas of CPP research are presented, whilst  raising relevant questions for further development. 

The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of CPPs, both in vitro and in vivo are discussed. Therapeutic potential of CPPs and commercial developments are discussed. 

The monograph is written for researchers and students in the field.

Classes and applications of CPP.- CPP functionalization.- Protein delivery and mimicry.- Targeting strategies.- Methods for detection and visualization of CPPs.- Methods for structural studies of CPPs.- Kinetics.- Toxicity and immune response.- Cell-translocation mechanisms of CPPs.- Clinical trials and commercialization using CPPs.- Therapeutic potential of CPPs.

Erscheinungsdatum
Zusatzinfo 15 Tables, color; 17 Illustrations, color; 8 Illustrations, black and white; XII, 470 p. 25 illus., 17 illus. in color.
Verlagsort Singapore
Sprache englisch
Maße 155 x 235 mm
Gewicht 887 g
Themenwelt Medizin / Pharmazie Pharmazie
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Genetik / Molekularbiologie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Schlagworte CPP processing • CPP uptake • Drug Delivery • Protein / peptide transduction domain • Trojan peptide
ISBN-10 981-13-8746-X / 981138746X
ISBN-13 978-981-13-8746-3 / 9789811387463
Zustand Neuware
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