Textbook of Diabetes

R. I. G. Holt, University of Southampton;

C. Cockram, Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China;

A. Flyvbjerg, University of Aarhus, Denmark;

B. J. Goldstein, Merck Research Laboratories, Rahway, NJ, USA

List of contributors

Preface to the Fifth Edition

List of Abbreviations

Part 1 Diabetes in its Historical and Social Context

1 The History of Diabetes
Robert B. Tattersall with David Matthews

2 The Classification and Diagnosis of Diabetes
Ambady Ramachandran, Chamukuttan Snehalatha, and Arun Nanditha

3 Epidemiology of Type 1 Diabetes Mellitus
Lars C. Stene and Jaakko Tuomilehto

4 Epidemiology of Type 2 Diabetes Mellitus
Ronald C.W. Ma and Peter C.Y. Tong

5 The Global Burden of Diabetes
Mohammed K. Ali, Karla I. Galaviz, Mary Beth Weber, and K.M. Venkat Narayan

Part 2 Normal Physiology

6 Islet Function and Insulin Secretion
Peter M. Jones and Shanta J. Persaud

7 Glucagon in Islet and Metabolic Regulation
David D'Alessio, Darleen Sandoval, and Jenny Tong

8 Mechanism of Insulin Action
Morris F. White

9 Control of Weight: How Do We Get Fat?
Arianne N. Sweeting and Ian D. Caterson

Part 3 Pathogenesis of Diabetes

10 Autoimmune Type 1 Diabetes
Shehab Alshiekh, Helena Elding Larsson, Sten-A. Ivarsson, and Åke Lernmark

11 Other Disorders with a Type 1 Diabetes Phenotype
Alice P.S. KongElaine Y.K. Chow, and Juliana C.N. Chan

12 Abnormalities of Insulin Secretion and ß-Cell Defects in Type 2 Diabetes
Stefano del Prato and Steven Kahn

13 Insulin Resistance in Type 2 Diabetes
Michael Roden, Kitt Petersen, and Gerald Shulman

14 The Genetic Architecture of Type 2 Diabetes
Rashmi B. Prasad and Leif Groop

15 Metabolic Disturbances in Diabetes
Adrian Vella and Robert A. Rizza

16 Obesity and Diabetes
Hans Hauner

17 The Microbiome and Diabetes
Amanda J. Cox, Nicholas P. West, and Allan W. Cripps

Part 4 Other Types of Diabetes

18 Monogenic Causes of Diabetes
Shivani Misra and Andrew T. Hattersley

19 Drug-Induced Diabetes
Charles Ponte and Devra Dang

20 Endocrine Disorders that Cause Diabetes
Rachel E. Jennings and Neil A. Hanley

21 Pancreatic Diseases and Diabetes
Ranjit Unnikrishnan and Viswanathan Mohan

Part 5 Managing the Patient with Diabetes [OK HERE]

22 Clinical Presentations of Diabetes
Ee Lin Lim and Roy Taylor

23 The Aims of Diabetes Care
Katharine D. Barnard and Richard I.G. Holt

24 Educating People with Diabetes
Ingrid Willaing and Michael Vallis

25 Lifestyle Issues: Diet
Nicola Guess

26 Lifestyle Issues: Exercise
Mimi Z. Chen and Robert C. Andrews

27 Monitoring Diabetes
Andrew J. Farmer

28 Drug Therapy: Special Considerations in Diabetes
Bernard M.Y. Cheung and Ronald C.W. Ma

Part 6 Treatment of Diabetes

29 Insulin and Insulin Treatment
Parth Narendran and Stephen Gough

30 New Technologies for Glucose Monitoring and Insulin Administration
David L. Horwitz and David C. Klonoff

31 Oral Glucose-Lowering Agents
Clifford J. Bailey and Andrew J. Krentz

32 Non-Insulin Parenteral Therapies
Tina Vilsbøll, Mikkel Christensen, Tina Jorsal, and Filip K. Knop

33 How to Use Type 2 Diabetes Treatments in Clinical Practice: Combination Therapies
Silvio Inzucchi and David Matthews

34 In-Hospital Treatment and Surgery in People with Diabetes
Ketan Dhatariya and June James

35 Hypoglycemia in Diabetes
Philip E. Cryer and Ana María Arbeláez

36 Acute Metabolic Complications of Diabetes: Diabetic Ketoacidosis and the Hyperosmolar Hyperglycemic State
Niels Møller

Part 7 Microvascular Complications in Diabetes

37 Pathogenesis of Microvascular Complications
Allan Flyvbjerg

38 Diabetic Retinopathy
Toke Bek

39 Diabetic Nephropathy
Sally M. Marshall and Allan Flyvbjerg

40 Diabetic Peripheral Neuropathy
Dan Ziegler

Part 8 Macrovascular Complications in Diabetes

41 The Pathogenesis of Macrovascular Complications
Stephen Gray, Elyse DiMarco, Riccardo Candido, Mark E. Cooper, and Karin A.M. Jandeleit-Dahm

42 Cardiovascular Risk Factors: Hypertension
Peter M. Nilsson

43 Diabetes and Risk of Cardiovascular Disease
Adie Viljoen Supriya Joshi, and Anthony S. Wierzbicki

44 Ischemic Heart Disease
Christoph H. Saely, Kourosh Vathie, and Heinz Drexel

45 Congestive Heart Failure
Anna Norhammar, Isabelle Johansson, Inga S. Thrainsdottir, and Lars Rydén

46 Cerebrovascular Disease
Colum F. Amory and Jesse Weinberger

47 Peripheral Vascular Disease
Henrik H. Sillesen

Part 9 Other Complications of Diabetes

48 Foot Problems in People with Diabetes
Andrew J.M. Boulton

49 Sexual Function in Men and Women with Diabetes
David Price

50 Gastrointestinal Manifestations of Diabetes Mellitus
Adil E. Bharucha and Michael Camilleri

51 Diabetes and Non-Alcoholic Fatty Liver Disease
Shivakumar Chitturi and Geoffrey C. Farrell

52 The Skin in Diabetes
Graham R. Sharpe and Paul D. Yesudian

53 Bone and Rheumatic Disorders in Diabetes
Andrew Grey and Nicola Dalbeth

54 Diabetes and Cancer
Ellena Badrick and Andrew Renehan

55 Diabetes and Infections
Clive S. Cockram and Bonnie C.K. Wong

Part 10 Psychosocial Aspects of Diabetes

56 Psychological Factors and Diabetes Mellitus
Frans Pouwer and Jane Speight

57 Psychiatric Disorders and Diabetes
Richard I.G. Holt and Les Citrome

58 Social Aspects of Diabetes
Brian M. Frier and Mark W.J. Strachan

Part 11 Diabetes in Special Groups

59 Diabetes in Childhood
Shideh Majidi, Christine M. Chan, and Marian Rewers

60 Diabetes in Adolescence and Transitional Care
Lori Laffel

61 Diabetes in Pregnancy
Timothy Cundy

62 Diabetes in Old Age
Ahmed H. Abdelhafiz and Alan J. Sinclair

63 Diabetes at the End of Life
June James, Jean MacLeod, and Robert Gregory

Part 12 Delivery and Organization of Diabetes Care

64 The Role of the Multidisciplinary Team Across Primary and Secondary Care
Samuel I. Seidu, Kamlesh Khunti, and Melanie J. Davies

65 Models of Diabetes Care Across Different Resource Settings
Naomi S. Levitt, Sam Surka, Andrew Farmer, and Bob Mash

Part 13 Future Directions

66 Future Drug Treatment for Type 1 Diabetes
Jennifer L. Sherr, Eda Cengiz, Michelle A. Van Name, Stuart A. Weinzimer, and William V. Tamborlane

67 Future Drug Treatments for Type 2 Diabetes
Clifford J. Bailey

68 Stem Cell Therapy in Diabetes
Angelo Avogaro and Gian Paolo Fadini

69 Islet Transplantation
Angela Koh, Peter E. Senior, and A.M. James Shapiro

70 Gene Therapy for Diabetes
Virginia Haurigot, Veronica Jimenez, and Fatima Bosch

71 Future Models of Diabetes Care
Sanjeev N. Mehta and Robert A. Gabbay

Index