The Duration and Safety of Osteoporosis Treatment (eBook)
XVI, 338 Seiten
Springer International Publishing (Verlag)
978-3-319-23639-1 (ISBN)
Providing a comprehensive review of short-and long-term adverse events of both antiresorptive and anabolic drugs, this practical guide updates the clinician on the pathophysiology of osteoporosis and the principles behind our present and future pharmaceuticals. Leading practitioners in the field examine all current literature and data regarding the duration and safety of these therapies, with recommendations for clinicians on decision-making and best practices for osteoporosis patients. An overview of the pathophysiology and epidemiology of osteoporosis and discussion of both anabolic and antiresorptive drugs is followed by fracture risk assessment and an examination of treatment failures. Next, a number of chapters are dedicated to the diagnosis, presentation and management of atypical femur fractures and osteonecrosis of the jaw (ONJ), each of which are significant patient concerns when using these osteoporosis treatments. The introduction and utilization of drug holidays is also discussed, as well as the long-term outlook for management of osteoporotic patients. Written and edited by experts in the field, The Duration and Safety of Osteoporosis Treatment is a balanced resource for researchers, practitioners and policy-makers alike for clinical decision-making and patient care.
Stuart L. Silverman, MD, FACP, FACR
Cedars-Sinai Medical Center
Division of Rheumatology
Department of Medicine
Los Angeles, CA, USA
University of California Los Angeles
David Geffen School of Medicine
Los Angeles, CA, USA
Bo Abrahamsen, MD, PhD
University of Southern Denmark
Odense Patient Data Explorative Network
Institute of Clinical Research
Odense, Denmark
Holbæk Hospital
Department of Medicine
Holbæk, Denmark
Stuart L. Silverman, MD, FACP, FACRCedars-Sinai Medical CenterDivision of RheumatologyDepartment of MedicineLos Angeles, CA, USAUniversity of California Los AngelesDavid Geffen School of MedicineLos Angeles, CA, USABo Abrahamsen, MD, PhDUniversity of Southern DenmarkOdense Patient Data Explorative NetworkInstitute of Clinical ResearchOdense, DenmarkHolbæk HospitalDepartment of MedicineHolbæk, Denmark
Foreword Juliet CompstonPrefaceChapter 1 Osteoporosis: Pathophysiology & Epidemiology Rebecca J. Moon, Cyrus Cooper, and Nicholas C. HarveyChapter 2 Antiresorptives R. Graham G. Russell, Maria K. Tsoumpra, Frank H. Ebetino, Michael PazianasChapter 3 Anabolics Erik Fink EriksenChapter 4 Tools for Assessing Fracture Risk and for Treatment Monitoring William D. Leslie, Lisa M. Lix, and Suzanne N. MorinChapter 5 Treatment Failure Elisa Torres del Pliego, Daniel Prieto-Alhambra, and Adolfo Díez-PerezChapter 6 Epidemiology of Atypical Subtrochanteric and Femoral Shaft Fractures Jeri W. NievesChapter 7 Bisphosphonate-Related Atypical Femoral Fractures and Their Radiographic Features Joseph C. Giaconi and C. Travis WattersonChapter 8 Factors Contributing to Atypical Femoral Fractures Adele L. Boskey and Marjolein C. H. van der MeulenChapter 9 Clinical Presentation of Atypical Femur Fractures Yelena Bogdan and Thomas A. EinhornChapter 10 Effects of Antiresorptive Therapy on Bone Microarchitecture Joy N. Tsai and Mary L. BouxseinChapter 11 Management of Atypical Femoral Fractures Joseph M. Lane, Libi Z. Galmer, David S. Wellman, Abigail L. Campbell, Jonathan E. JoChapter 12 Osteonecrosis of the Jaw: Clinico-Pathologic and Radiologic Features Parish P. Sedghizadeh and Allan C. JonesChapter 13 Epidemiology of Osteonecrosis of the Jaws from Antiresorptive Treatment Morten SchiødtChapter 14 Management of Osteonecrosis of the Jaw in Patients Receiving Antiresorptive Treatment Morten SchiødtChapter 15 Long-Term Efficacy and Safety of Treatments for Osteoporosis Socrates E. PapapoulosChapter 16 Management of Drug Holidays Christian Roux and Karine BriotChapter 17 Patients Who Do Not Take Their Osteoporosis Medications: Can We Help Them Become Compliant? Deborah T. GoldChapter 18 Fractures and Healing on Antiresorptive Therapy Eli Kupperman and Susan V. BukataChapter 19 Antiresorptive Therapy and Mortality and Cancer Incidence Peter VestergaardChapter 20 Other Safety Concerns Michael R. McClungChapter 21 The Impact of Regulatory and Scientific Organizations Recommendations on Clinical Decision Making Alexandra Papaioannou, Arnav Agarwal, and Sarah KarampatosChapter 22 Integrated Clinical View on Long-Term Management of Patients with Osteoporosis E. Michael LewieckiChapter 23 Conclusions Stuart L. Silverman and Bo Abrahamsen
Erscheint lt. Verlag | 29.12.2015 |
---|---|
Zusatzinfo | XVI, 338 p. 100 illus., 38 illus. in color. |
Verlagsort | Cham |
Sprache | englisch |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete |
Schlagworte | Anabolic therapy • Antiresorptive therapy • Atypical femur fracture • Bisphosphonates • Bone microarchitecture • Drug holiday • Fracture risk assessment • Osteonecrosis of the jaw • Osteoporosis treatment |
ISBN-10 | 3-319-23639-3 / 3319236393 |
ISBN-13 | 978-3-319-23639-1 / 9783319236391 |
Haben Sie eine Frage zum Produkt? |
Größe: 13,3 MB
DRM: Digitales Wasserzeichen
Dieses eBook enthält ein digitales Wasserzeichen und ist damit für Sie personalisiert. Bei einer missbräuchlichen Weitergabe des eBooks an Dritte ist eine Rückverfolgung an die Quelle möglich.
Dateiformat: PDF (Portable Document Format)
Mit einem festen Seitenlayout eignet sich die PDF besonders für Fachbücher mit Spalten, Tabellen und Abbildungen. Eine PDF kann auf fast allen Geräten angezeigt werden, ist aber für kleine Displays (Smartphone, eReader) nur eingeschränkt geeignet.
Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.
Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.
aus dem Bereich