The Duration and Safety of Osteoporosis Treatment -

The Duration and Safety of Osteoporosis Treatment

Anabolic and Antiresorptive Therapy
Buch | Softcover
XVI, 338 Seiten
2016 | 1st ed. 2016
Springer International Publishing (Verlag)
978-3-319-23638-4 (ISBN)
106,99 inkl. MwSt

Providing a comprehensive review of short-and long-term adverse events of both antiresorptive and anabolic drugs, this practical guide updates the clinician on the pathophysiology of osteoporosis and the principles behind our present and future pharmaceuticals. Leading practitioners in the field examine all current literature and data regarding the duration and safety of these therapies, with recommendations for clinicians on decision-making and best practices for osteoporosis patients. An overview of the pathophysiology and epidemiology of osteoporosis and discussion of both anabolic and antiresorptive drugs is followed by fracture risk assessment and an examination of treatment failures. Next, a number of chapters are dedicated to the diagnosis, presentation and management of atypical femur fractures and osteonecrosis of the jaw (ONJ), each of which are significant patient concerns when using these osteoporosis treatments. The introduction and utilization of drug holidays is alsodiscussed, as well as the long-term outlook for management of osteoporotic patients. Written and edited by experts in the field, The Duration and Safety of Osteoporosis Treatment is a balanced resource for researchers, practitioners and policy-makers alike for clinical decision-making and patient care. 

Stuart L. Silverman, MD, FACP, FACRCedars-Sinai Medical CenterDivision of RheumatologyDepartment of MedicineLos Angeles, CA, USAUniversity of California Los AngelesDavid Geffen School of MedicineLos Angeles, CA, USABo Abrahamsen, MD, PhDUniversity of Southern DenmarkOdense Patient Data Explorative NetworkInstitute of Clinical ResearchOdense, DenmarkHolbæk HospitalDepartment of MedicineHolbæk, Denmark

Foreword.- Preface.- Osteoporosis: Pathophysiology & Epidemiology.- Antiresorptives.- Anabolics.- Tools for Assessing Fracture Risk and for Treatment Monitoring.- Treatment Failure.- Epidemiology of Atypical Subtrochanteric and Femoral Shaft Fractures.- Bisphosphonate-Related Atypical Femoral Fractures and Their Radiographic Features.- Factors Contributing to Atypical Femoral Fractures.- Clinical Presentation of Atypical Femur Fractures.- Effects of Antiresorptive Therapy on Bone Microarchitecture.- Management of Atypical Femoral Fractures.- Osteonecrosis of the Jaw: Clinico-Pathologic and Radiologic Features.- Epidemiology of Osteonecrosis of the Jaws from Antiresorptive Treatment.- Management of Osteonecrosis of the Jaw in Patients Receiving Antiresorptive Treatment.- Long-Term Efficacy and Safety of Treatments for Osteoporosis.- Management of Drug Holidays.- Patients Who Do Not Take Their Osteoporosis Medications:  Can We Help Them Become Compliant?.- Fractures andHealing on Antiresorptive Therapy.- Antiresorptive Therapy and Mortality and Cancer Incidence.- Other Safety Concerns.- The Impact of Regulatory and Scientific Organizations Recommendations on Clinical Decision Making.- Integrated Clinical View on Long-Term Management of Patients with Osteoporosis.- Conclusions.

Erscheint lt. Verlag 8.1.2016
Zusatzinfo XVI, 338 p. 100 illus., 38 illus. in color.
Verlagsort Cham
Sprache englisch
Maße 178 x 254 mm
Themenwelt Medizinische Fachgebiete Chirurgie Unfallchirurgie / Orthopädie
Medizinische Fachgebiete Innere Medizin Endokrinologie
Schlagworte Anabolic therapy • Antiresorptive therapy • Atypical femur fracture • Bisphosphonates • Bone microarchitecture • Drug holiday • endocrinology • Fracture risk assessment • Medicine • Orthopedics • Osteonecrosis of the jaw • Osteoporosis treatment
ISBN-10 3-319-23638-5 / 3319236385
ISBN-13 978-3-319-23638-4 / 9783319236384
Zustand Neuware
Haben Sie eine Frage zum Produkt?
Mehr entdecken
aus dem Bereich
für Studium und Praxis unter Berücksichtigung des …

von Markus Müller; Achim Elsen; Matthias Eppinger

Buch | Softcover (2022)
Medizinische Vlgs- u. Inform.-Dienste (Verlag)
28,00