Developing Brain Behaviour -

Developing Brain Behaviour (eBook)

The Role of Lipids in Infant Formula

John Dobbing (Herausgeber)

eBook Download: PDF
1997 | 1. Auflage
537 Seiten
Elsevier Science (Verlag)
978-0-08-053037-6 (ISBN)
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Certain long chain polyunsaturated fatty acids (LCPUFAs) are thought to be essential components of the nutrition of infants, including those prematurely born, in the sense that they cannot be synthesises by the immature organism and must therefore be supplied in the diet. Breast milk contains these substances, but many manufactured infant formulae do not.
An absence of dietary LCPUFAs has been thought to affect the development of the brain and retina, possibly leading to abnormalties in cognitive and visual function. Considerable multidisciplinary research has been carried out to investigate this proposition. Diets free from LCPUFAs have been compared with supplemented formulae, or with breast milk.
The conclusions from this research were critically examined by a group of leading paediatricians, nutritionists, experts in visual science and developmental behavioural scientists at a 'Dobbing Workshop' held in the United States in late February, 1997. Each of the Chapters was precirculated to the whole group, commented on before the Workshop, and then exhaustively discussed. The Chapters and Commentaries which are published here have therefore undergone a more extensive peer-review process than is usually the case.
Certain long chain polyunsaturated fatty acids (LCPUFAs) are thought to be essential components of the nutrition of infants, including those prematurely born, in the sense that they cannot be synthesises by the immature organism and must therefore be supplied in the diet. Breast milk contains these substances, but many manufactured infant formulae do not.An absence of dietary LCPUFAs has been thought to affect the development of the brain and retina, possibly leading to abnormalties in cognitive and visual function. Considerable multidisciplinary research has been carried out to investigate this proposition. Diets free from LCPUFAs have been compared with supplemented formulae, or with breast milk.The conclusions from this research were critically examined by a group of leading paediatricians, nutritionists, experts in visual science and developmental behavioural scientists at a 'Dobbing Workshop' held in the United States in late February, 1997. Each of the Chapters was precirculated to the whole group, commented on before the Workshop, and then exhaustively discussed. The Chapters and Commentaries which are published here have therefore undergone a more extensive peer-review process than is usually the case.

Front Cover 1
Developing Brain and Behaviour: The Role of Lipids in Infant Formula 4
Copyright Page 5
Contents 6
List of Contributors 8
Dobbing Workshops 10
Preface 12
Part 1: Clinical Studies 18
Chapter 1. Long-chain polyunsaturated fatty acids, infant feeding and cognitive development 20
Chapter 2. Long-chain polyunsaturated fatty acid supplementation of preterm infants 58
Chapter 3. Polyunsaturated fatty acid nutrition in infants born at term 120
Chapter 4. Statistically significant versus biologically significant effects of long-chain polyunsaturated fatty acids on growth 186
Part 2: Methodology: Clinical Studies 224
Chapter 5. Methodological considerations in longitudinal studies of infant risk 226
Chapter 6. Grating acuity cards: validity and reliability in studies of human visual development 270
Part 3: Behavioural Science Considerations 310
Chapter 7. Long-chain polyunsaturated fatty acids and the measurement and prediction of intelligence (IQ) 312
Chapter 8. Individual differences in infant cognition: methods, measures, and models 356
Chapter 9. Early nutrition and behavior: a conceptual framework for critical analysis of research 404
Chapter 10. The effects of early diet on synaptic function and behavior: pitfalls and potentials 444
Appendices: General Commentary on Behavioural Science Implications and Methodology 490
Appendix A: Nutrition and development- observations and implications 492
Appendix B: Design, measurement, and statistical approaches 528
Appendix C: General commentary 534
Index 546

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