Evidence Based Pathology and Laboratory Medicine (eBook)
XIV, 361 Seiten
Springer New York (Verlag)
978-1-4419-1030-1 (ISBN)
Focusing on practical, patient related issues, this volume provides the basic concepts of Evidence Based Medicine (EBM) as they relate to Pathology and Laboratory Medicine and presents various practical applications. It includes EBM concepts for use in the identification of cost-effective panels of immunostains and other laboratory tests and for improvement of diagnostic accuracy based on the identification of selected diagnostic features for particular differential diagnosis. EBM concepts are also put forth for use in Meta-analysis to integrate the results of conflicting literature reports and use of novel analytical tools such as Bayesian belief networks, neural networks, multivariate statistics and decision tree analysis for the development of new diagnostic and prognostic models for the evaluation of patients. This volume will be of great value to pathologists who will benefit from the concepts being promoted by EBM, such as levels of evidence, use of Bayesian statistics to develop diagnostic and other rules and stronger reliance on 'hard data' to support therapeutic and diagnostic modalities.
Focusing on practical, patient related issues, this volume provides the basic concepts of Evidence Based Medicine (EBM) as they relate to Pathology and Laboratory Medicine and presents various practical applications. It includes EBM concepts for use in the identification of cost-effective panels of immunostains and other laboratory tests and for improvement of diagnostic accuracy based on the identification of selected diagnostic features for particular differential diagnosis. EBM concepts are also put forth for use in Meta-analysis to integrate the results of conflicting literature reports and use of novel analytical tools such as Bayesian belief networks, neural networks, multivariate statistics and decision tree analysis for the development of new diagnostic and prognostic models for the evaluation of patients. This volume will be of great value to pathologists who will benefit from the concepts being promoted by EBM, such as levels of evidence, use of Bayesian statistics to develop diagnostic and other rules and stronger reliance on "e;hard data"e; to support therapeutic and diagnostic modalities.
Table of ContentsPrefaceContributorsI. The Problem and Available Resources1. Introduction to Evidence-Based Pathology and Laboratory Medicine Alberto M. Marchevsky and Mark Wick. Evidence-Based Pathology: A Stable Set of Principles for a Rapidly Evolving Specialty José Costa and Sarah Whitaker3. What Is Best Evidence in Pathology?Peter J. Saunders and Christopher N. Otis4. Biostatistics 101Robin T. Vollmer5. Prognostication and Prediction in Anatomic Pathology: Carcinoma of the Breast as an Illustrative ModelMark R. Wick and Alberto M. Marchevsky6. Principles of Classification and Diagnosis in Anatomic Pathology and the Inevitability of Problem CasesMichael Hendrickson7. Evaluating Oncopathological Studies: The Need to Evaluate the Internal and External Validity of Study ResultsMichael Hendrickson and Bonnie Balzer8. Power Analysis and Sample Sizes in Pathology ResearchRobin T. Vollmer9. Meta-Analysis: A Statistical Method to Integrate Information Provided by Different Studies Eleftherios C. Vamvakas10. Decision Analysis and Decision Support Systems in Anatomic PathologyMichael Hendrickson and Bonnie BalzerII. Solutions Offered by Evidence-Based Pathology and Laboratory Medicine11. Evidence-Based Approach to Evaluate Information Published in the Pathology Literature and Integrate It with Personal Experience Alberto M. Marchevsky and Mark Wick12. Evidence-Based Cell Pathology Re-visited: A Personal ViewKenneth Fleming13. Development of Evidence-Based Diagnostic Criteria and Prognostic/Predictive Models: Experience at Cedars Sinai Medical CenterAlberto M. Marchevsky and Ruta Gupta14. Evaluation and Reduction of Diagnostic Errors in Pathology Using an Evidence-Based ApproachRaouf E. Nakhleh15. Metaanalysis 101 for PathologistsRuta Gupta and Alberto M. Marchevsky16. Evidence-Based Practices in Applied Immunohistochemistry: Dilemmas Caused by Cross-PurposesMark R. Wick, Paul E. Swanson, and Alberto M. Marchevsky17. Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into PracticeJia-Perng Jennifer Wei and Wayne W. Grody18. The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory EvidenceJi Yeon Kim, Elizabeth M. Van Cott, and Kent B. Lewandrowski19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Stacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex José Costa and Sarah Whitaker3. What Is Best Evidence in Pathology?Peter J. Saunders and Christopher N. Otis4. Biostatistics 101Robin T. Vollmer5. Prognostication and Prediction in Anatomic Pathology: Carcinoma of the Breast as an Illustrative ModelMark R. Wick and Alberto M. Marchevsky6. Principles of Classification and Diagnosis in Anatomic Pathology and the Inevitability of Problem CasesMichael Hendrickson7. Evaluating Oncopathological Studies: The Need to Evaluate the Internal and External Validity of Study ResultsMichael Hendrickson and Bonnie Balzer8. Power Analysis and Sample Sizes in Pathology ResearchRobin T. Vollmer9. Meta-Analysis: A Statistical Method to Integrate Information Provided by Different Studies Eleftherios C. Vamvakas10. Decision Analysis and Decision Support Systems in Anatomic PathologyMichael Hendrickson and Bonnie BalzerII. Solutions Offered by Evidence-Based Pathology and Laboratory Medicine11. Evidence-Based Approach to Evaluate Information Published in the Pathology Literature and Integrate It with Personal Experience Alberto M. Marchevsky and Mark Wick12. Evidence-Based Cell Pathology Re-visited: A Personal ViewKenneth Fleming13. Development of Evidence-Based Diagnostic Criteria and Prognostic/Predictive Models: Experience at Cedars Sinai Medical CenterAlberto M. Marchevsky and Ruta Gupta14. Evaluation and Reduction of Diagnostic Errors in Pathology Using an Evidence-Based ApproachRaouf E. Nakhleh15. Metaanalysis 101 for PathologistsRuta Gupta and Alberto M. Marchevsky16. Evidence-Based Practices in Applied Immunohistochemistry: Dilemmas Caused by Cross-PurposesMark R. Wick, Paul E. Swanson, and Alberto M. Marchevsky17. Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into PracticeJia-Perng Jennifer Wei and Wayne W. Grody18. The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory EvidenceJi Yeon Kim, Elizabeth M. Van Cott, and Kent B. Lewandrowski19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Stacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Peter J. Saunders and Christopher N. Otis4. Biostatistics 101Robin T. Vollmer5. Prognostication and Prediction in Anatomic Pathology: Carcinoma of the Breast as an Illustrative ModelMark R. Wick and Alberto M. Marchevsky6. Principles of Classification and Diagnosis in Anatomic Pathology and the Inevitability of Problem CasesMichael Hendrickson7. Evaluating Oncopathological Studies: The Need to Evaluate the Internal and External Validity of Study ResultsMichael Hendrickson and Bonnie Balzer8. Power Analysis and Sample Sizes in Pathology ResearchRobin T. Vollmer9. Meta-Analysis: A Statistical Method to Integrate Information Provided by Different Studies Eleftherios C. Vamvakas10. Decision Analysis and Decision Support Systems in Anatomic PathologyMichael Hendrickson and Bonnie BalzerII. Solutions Offered by Evidence-Based Pathology and Laboratory Medicine11. Evidence-Based Approach to Evaluate Information Published in the Pathology Literature and Integrate It with Personal Experience Alberto M. Marchevsky and Mark Wick12. Evidence-Based Cell Pathology Re-visited: A Personal ViewKenneth Fleming13. Development of Evidence-Based Diagnostic Criteria and Prognostic/Predictive Models: Experience at Cedars Sinai Medical CenterAlberto M. Marchevsky and Ruta Gupta14. Evaluation and Reduction of Diagnostic Errors in Pathology Using an Evidence-Based ApproachRaouf E. Nakhleh15. Metaanalysis 101 for PathologistsRuta Gupta and Alberto M. Marchevsky16. Evidence-Based Practices in Applied Immunohistochemistry: Dilemmas Caused by Cross-PurposesMark R. Wick, Paul E. Swanson, and Alberto M. Marchevsky17. Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into PracticeJia-Perng Jennifer Wei and Wayne W. Grody18. The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory EvidenceJi Yeon Kim, Elizabeth M. Van Cott, and Kent B. Lewandrowski19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Stacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Mark R. Wick and Alberto M. Marchevsky6. Principles of Classification and Diagnosis in Anatomic Pathology and the Inevitability of Problem CasesMichael Hendrickson7. Evaluating Oncopathological Studies: The Need to Evaluate the Internal and External Validity of Study ResultsMichael Hendrickson and Bonnie Balzer8. Power Analysis and Sample Sizes in Pathology ResearchRobin T. Vollmer9. Meta-Analysis: A Statistical Method to Integrate Information Provided by Different Studies Eleftherios C. Vamvakas10. Decision Analysis and Decision Support Systems in Anatomic PathologyMichael Hendrickson and Bonnie BalzerII. Solutions Offered by Evidence-Based Pathology and Laboratory Medicine11. Evidence-Based Approach to Evaluate Information Published in the Pathology Literature and Integrate It with Personal Experience Alberto M. Marchevsky and Mark Wick12. Evidence-Based Cell Pathology Re-visited: A Personal ViewKenneth Fleming13. Development of Evidence-Based Diagnostic Criteria and Prognostic/Predictive Models: Experience at Cedars Sinai Medical CenterAlberto M. Marchevsky and Ruta Gupta14. Evaluation and Reduction of Diagnostic Errors in Pathology Using an Evidence-Based ApproachRaouf E. Nakhleh15. Metaanalysis 101 for PathologistsRuta Gupta and Alberto M. Marchevsky16. Evidence-Based Practices in Applied Immunohistochemistry: Dilemmas Caused by Cross-PurposesMark R. Wick, Paul E. Swanson, and Alberto M. Marchevsky17. Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into PracticeJia-Perng Jennifer Wei and Wayne W. Grody18. The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory EvidenceJi Yeon Kim, Elizabeth M. Van Cott, and Kent B. Lewandrowski19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Stacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex 13. Development of Evidence-Based Diagnostic Criteria and Prognostic/Predictive Models: Experience at Cedars Sinai Medical CenterAlberto M. Marchevsky and Ruta Gupta14. Evaluation and Reduction of Diagnostic Errors in Pathology Using an Evidence-Based ApproachRaouf E. Nakhleh15. Metaanalysis 101 for PathologistsRuta Gupta and Alberto M. Marchevsky16. Evidence-Based Practices in Applied Immunohistochemistry: Dilemmas Caused by Cross-PurposesMark R. Wick, Paul E. Swanson, and Alberto M. Marchevsky17. Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into PracticeJia-Perng Jennifer Wei and Wayne W. Grody18. The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory EvidenceJi Yeon Kim, Elizabeth M. Van Cott, and Kent B. Lewandrowski19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Stacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Mark R. Wick, Paul E. Swanson, and Alberto M. Marchevsky17. Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into PracticeJia-Perng Jennifer Wei and Wayne W. Grody18. The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory EvidenceJi Yeon Kim, Elizabeth M. Van Cott, and Kent B. Lewandrowski19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Stacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Mark R. Wick and Elliott FoucarIndex 19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Stacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex Mark R. Wick and Elliott FoucarIndex
| Erscheint lt. Verlag | 1.7.2011 |
|---|---|
| Zusatzinfo | XIV, 361 p. 137 illus., 99 illus. in color. |
| Verlagsort | New York |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Laboratoriumsmedizin |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie | |
| Studium ► 2. Studienabschnitt (Klinik) ► Pathologie | |
| Studium ► Querschnittsbereiche ► Prävention / Gesundheitsförderung | |
| Sozialwissenschaften ► Politik / Verwaltung | |
| Schlagworte | Bayesian Statistics • immunostains • laboratory tests • Meta-analysis • Neural networks |
| ISBN-10 | 1-4419-1030-1 / 1441910301 |
| ISBN-13 | 978-1-4419-1030-1 / 9781441910301 |
| Haben Sie eine Frage zum Produkt? |
PDF (Wasserzeichen)Größe: 29,0 MB
DRM: Digitales Wasserzeichen
Dieses eBook enthält ein digitales Wasserzeichen und ist damit für Sie personalisiert. Bei einer missbräuchlichen Weitergabe des eBooks an Dritte ist eine Rückverfolgung an die Quelle möglich.
Dateiformat: PDF (Portable Document Format)
Mit einem festen Seitenlayout eignet sich die PDF besonders für Fachbücher mit Spalten, Tabellen und Abbildungen. Eine PDF kann auf fast allen Geräten angezeigt werden, ist aber für kleine Displays (Smartphone, eReader) nur eingeschränkt geeignet.
Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.
Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.
aus dem Bereich
