Evidence Based Pathology and Laboratory Medicine -

Evidence Based Pathology and Laboratory Medicine (eBook)

eBook Download: PDF
2011 | 2011
XIV, 361 Seiten
Springer New York (Verlag)
978-1-4419-1030-1 (ISBN)
Systemvoraussetzungen
106,99 inkl. MwSt
  • Download sofort lieferbar
  • Zahlungsarten anzeigen

Focusing on practical, patient related issues, this volume provides the basic concepts of Evidence Based Medicine (EBM) as they relate to Pathology and Laboratory Medicine and presents various practical applications. It includes EBM concepts for use in the identification of cost-effective panels of immunostains and other laboratory tests and for improvement of diagnostic accuracy based on the identification of selected diagnostic features for particular differential diagnosis. EBM concepts are also put forth for use in Meta-analysis to integrate the results of conflicting literature reports and use of novel analytical tools such as Bayesian belief networks, neural networks, multivariate statistics and decision tree analysis for the development of new diagnostic and prognostic models for the evaluation of patients. This volume will be of great value to pathologists who will benefit from the concepts being promoted by EBM, such as levels of evidence, use of Bayesian statistics to develop diagnostic and other rules and stronger reliance on 'hard data' to support therapeutic and diagnostic modalities.


Focusing on practical, patient related issues, this volume provides the basic concepts of Evidence Based Medicine (EBM) as they relate to Pathology and Laboratory Medicine and presents various practical applications. It includes EBM concepts for use in the identification of cost-effective panels of immunostains and other laboratory tests and for improvement of diagnostic accuracy based on the identification of selected diagnostic features for particular differential diagnosis. EBM concepts are also put forth for use in Meta-analysis to integrate the results of conflicting literature reports and use of novel analytical tools such as Bayesian belief networks, neural networks, multivariate statistics and decision tree analysis for the development of new diagnostic and prognostic models for the evaluation of patients. This volume will be of great value to pathologists who will benefit from the concepts being promoted by EBM, such as levels of evidence, use of Bayesian statistics to develop diagnostic and other rules and stronger reliance on "e;hard data"e; to support therapeutic and diagnostic modalities.

Table of ContentsPrefaceContributorsI. The Problem and Available Resources1. Introduction to Evidence-Based Pathology and Laboratory Medicine Alberto M. Marchevsky and Mark Wick. Evidence-Based Pathology: A Stable Set of Principles for a Rapidly Evolving Specialty José Costa and Sarah Whitaker3. What Is Best Evidence in Pathology?Peter J. Saunders and Christopher N. Otis4. Biostatistics 101Robin T. Vollmer5. Prognostication and Prediction in Anatomic Pathology: Carcinoma of the Breast as an Illustrative ModelMark R. Wick and Alberto M. Marchevsky6. Principles of Classification and Diagnosis in Anatomic Pathology and the Inevitability of Problem CasesMichael Hendrickson7. Evaluating Oncopathological Studies: The Need to Evaluate the Internal and External Validity of Study ResultsMichael Hendrickson and Bonnie Balzer8. Power Analysis and Sample Sizes in Pathology ResearchRobin T. Vollmer9. Meta-Analysis: A Statistical Method to Integrate Information Provided by Different Studies Eleftherios C. Vamvakas10. Decision Analysis and Decision Support Systems in Anatomic PathologyMichael Hendrickson and Bonnie BalzerII. Solutions Offered by Evidence-Based Pathology and Laboratory Medicine11. Evidence-Based Approach to Evaluate Information Published in the Pathology Literature and Integrate It with Personal Experience Alberto M. Marchevsky and Mark Wick12. Evidence-Based Cell Pathology Re-visited:  A Personal ViewKenneth Fleming13. Development of Evidence-Based Diagnostic Criteria and Prognostic/Predictive Models: Experience at Cedars Sinai Medical CenterAlberto M. Marchevsky and Ruta Gupta14. Evaluation and Reduction of Diagnostic Errors in Pathology Using an Evidence-Based ApproachRaouf E. Nakhleh15. Metaanalysis 101 for PathologistsRuta Gupta and Alberto M. Marchevsky16. Evidence-Based Practices in Applied Immunohistochemistry: Dilemmas Caused by Cross-PurposesMark R. Wick, Paul E. Swanson, and Alberto M. Marchevsky17. Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into PracticeJia-Perng Jennifer Wei and Wayne W. Grody18. The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory EvidenceJi Yeon Kim, Elizabeth M. Van Cott, and Kent B. Lewandrowski19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Stacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  José Costa and Sarah Whitaker3. What Is Best Evidence in Pathology?Peter J. Saunders and Christopher N. Otis4. Biostatistics 101Robin T. Vollmer5. Prognostication and Prediction in Anatomic Pathology: Carcinoma of the Breast as an Illustrative ModelMark R. Wick and Alberto M. Marchevsky6. Principles of Classification and Diagnosis in Anatomic Pathology and the Inevitability of Problem CasesMichael Hendrickson7. Evaluating Oncopathological Studies: The Need to Evaluate the Internal and External Validity of Study ResultsMichael Hendrickson and Bonnie Balzer8. Power Analysis and Sample Sizes in Pathology ResearchRobin T. Vollmer9. Meta-Analysis: A Statistical Method to Integrate Information Provided by Different Studies Eleftherios C. Vamvakas10. Decision Analysis and Decision Support Systems in Anatomic PathologyMichael Hendrickson and Bonnie BalzerII. Solutions Offered by Evidence-Based Pathology and Laboratory Medicine11. Evidence-Based Approach to Evaluate Information Published in the Pathology Literature and Integrate It with Personal Experience Alberto M. Marchevsky and Mark Wick12. Evidence-Based Cell Pathology Re-visited:  A Personal ViewKenneth Fleming13. Development of Evidence-Based Diagnostic Criteria and Prognostic/Predictive Models: Experience at Cedars Sinai Medical CenterAlberto M. Marchevsky and Ruta Gupta14. Evaluation and Reduction of Diagnostic Errors in Pathology Using an Evidence-Based ApproachRaouf E. Nakhleh15. Metaanalysis 101 for PathologistsRuta Gupta and Alberto M. Marchevsky16. Evidence-Based Practices in Applied Immunohistochemistry: Dilemmas Caused by Cross-PurposesMark R. Wick, Paul E. Swanson, and Alberto M. Marchevsky17. Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into PracticeJia-Perng Jennifer Wei and Wayne W. Grody18. The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory EvidenceJi Yeon Kim, Elizabeth M. Van Cott, and Kent B. Lewandrowski19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Stacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Peter J. Saunders and Christopher N. Otis4. Biostatistics 101Robin T. Vollmer5. Prognostication and Prediction in Anatomic Pathology: Carcinoma of the Breast as an Illustrative ModelMark R. Wick and Alberto M. Marchevsky6. Principles of Classification and Diagnosis in Anatomic Pathology and the Inevitability of Problem CasesMichael Hendrickson7. Evaluating Oncopathological Studies: The Need to Evaluate the Internal and External Validity of Study ResultsMichael Hendrickson and Bonnie Balzer8. Power Analysis and Sample Sizes in Pathology ResearchRobin T. Vollmer9. Meta-Analysis: A Statistical Method to Integrate Information Provided by Different Studies Eleftherios C. Vamvakas10. Decision Analysis and Decision Support Systems in Anatomic PathologyMichael Hendrickson and Bonnie BalzerII. Solutions Offered by Evidence-Based Pathology and Laboratory Medicine11. Evidence-Based Approach to Evaluate Information Published in the Pathology Literature and Integrate It with Personal Experience Alberto M. Marchevsky and Mark Wick12. Evidence-Based Cell Pathology Re-visited:  A Personal ViewKenneth Fleming13. Development of Evidence-Based Diagnostic Criteria and Prognostic/Predictive Models: Experience at Cedars Sinai Medical CenterAlberto M. Marchevsky and Ruta Gupta14. Evaluation and Reduction of Diagnostic Errors in Pathology Using an Evidence-Based ApproachRaouf E. Nakhleh15. Metaanalysis 101 for PathologistsRuta Gupta and Alberto M. Marchevsky16. Evidence-Based Practices in Applied Immunohistochemistry: Dilemmas Caused by Cross-PurposesMark R. Wick, Paul E. Swanson, and Alberto M. Marchevsky17. Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into PracticeJia-Perng Jennifer Wei and Wayne W. Grody18. The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory EvidenceJi Yeon Kim, Elizabeth M. Van Cott, and Kent B. Lewandrowski19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Stacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Mark R. Wick and Alberto M. Marchevsky6. Principles of Classification and Diagnosis in Anatomic Pathology and the Inevitability of Problem CasesMichael Hendrickson7. Evaluating Oncopathological Studies: The Need to Evaluate the Internal and External Validity of Study ResultsMichael Hendrickson and Bonnie Balzer8. Power Analysis and Sample Sizes in Pathology ResearchRobin T. Vollmer9. Meta-Analysis: A Statistical Method to Integrate Information Provided by Different Studies Eleftherios C. Vamvakas10. Decision Analysis and Decision Support Systems in Anatomic PathologyMichael Hendrickson and Bonnie BalzerII. Solutions Offered by Evidence-Based Pathology and Laboratory Medicine11. Evidence-Based Approach to Evaluate Information Published in the Pathology Literature and Integrate It with Personal Experience Alberto M. Marchevsky and Mark Wick12. Evidence-Based Cell Pathology Re-visited:  A Personal ViewKenneth Fleming13. Development of Evidence-Based Diagnostic Criteria and Prognostic/Predictive Models: Experience at Cedars Sinai Medical CenterAlberto M. Marchevsky and Ruta Gupta14. Evaluation and Reduction of Diagnostic Errors in Pathology Using an Evidence-Based ApproachRaouf E. Nakhleh15. Metaanalysis 101 for PathologistsRuta Gupta and Alberto M. Marchevsky16. Evidence-Based Practices in Applied Immunohistochemistry: Dilemmas Caused by Cross-PurposesMark R. Wick, Paul E. Swanson, and Alberto M. Marchevsky17. Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into PracticeJia-Perng Jennifer Wei and Wayne W. Grody18. The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory EvidenceJi Yeon Kim, Elizabeth M. Van Cott, and Kent B. Lewandrowski19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Stacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  13. Development of Evidence-Based Diagnostic Criteria and Prognostic/Predictive Models: Experience at Cedars Sinai Medical CenterAlberto M. Marchevsky and Ruta Gupta14. Evaluation and Reduction of Diagnostic Errors in Pathology Using an Evidence-Based ApproachRaouf E. Nakhleh15. Metaanalysis 101 for PathologistsRuta Gupta and Alberto M. Marchevsky16. Evidence-Based Practices in Applied Immunohistochemistry: Dilemmas Caused by Cross-PurposesMark R. Wick, Paul E. Swanson, and Alberto M. Marchevsky17. Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into PracticeJia-Perng Jennifer Wei and Wayne W. Grody18. The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory EvidenceJi Yeon Kim, Elizabeth M. Van Cott, and Kent B. Lewandrowski19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Stacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Mark R. Wick, Paul E. Swanson, and Alberto M. Marchevsky17. Evidence-Based Pathology and Laboratory Medicine in the Molecular Pathology Era: Transition of Tests from the Research Bench into PracticeJia-Perng Jennifer Wei and Wayne W. Grody18. The Use of Decision Analysis Tools for the Selection of Clinical Laboratory Tests: Developing Diagnostic and Forecasting Models Using Laboratory EvidenceJi Yeon Kim, Elizabeth M. Van Cott, and Kent B. Lewandrowski19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Stacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Mark R. Wick and Elliott FoucarIndex  19. Implementation and Benefits of Computerized Physician Order Entry and Evidence-Based Clinical Decision Support SystemsStacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Stacy E. F. Melanson, Aileen P. Morrison, David W. Bates, and Milenko J. Tanasijevic 20. Evidence-Based Pathology and Tort Law: How Do They Compare?Mark R. Wick and Elliott FoucarIndex  Mark R. Wick and Elliott FoucarIndex  

Erscheint lt. Verlag 1.7.2011
Zusatzinfo XIV, 361 p. 137 illus., 99 illus. in color.
Verlagsort New York
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Laboratoriumsmedizin
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Studium 2. Studienabschnitt (Klinik) Pathologie
Studium Querschnittsbereiche Prävention / Gesundheitsförderung
Sozialwissenschaften Politik / Verwaltung
Schlagworte Bayesian Statistics • immunostains • laboratory tests • Meta-analysis • Neural networks
ISBN-10 1-4419-1030-1 / 1441910301
ISBN-13 978-1-4419-1030-1 / 9781441910301
Haben Sie eine Frage zum Produkt?
PDFPDF (Wasserzeichen)
Größe: 29,0 MB

DRM: Digitales Wasserzeichen
Dieses eBook enthält ein digitales Wasser­zeichen und ist damit für Sie persona­lisiert. Bei einer missbräuch­lichen Weiter­gabe des eBooks an Dritte ist eine Rück­ver­folgung an die Quelle möglich.

Dateiformat: PDF (Portable Document Format)
Mit einem festen Seiten­layout eignet sich die PDF besonders für Fach­bücher mit Spalten, Tabellen und Abbild­ungen. Eine PDF kann auf fast allen Geräten ange­zeigt werden, ist aber für kleine Displays (Smart­phone, eReader) nur einge­schränkt geeignet.

Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.

Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.

Mehr entdecken
aus dem Bereich
Das Lehrbuch für das Medizinstudium

von Florian Horn

eBook Download (2020)
Georg Thieme Verlag KG
69,99
Das Lehrbuch für das Medizinstudium

von Florian Horn

eBook Download (2020)
Georg Thieme Verlag KG
69,99