Laboratory Animal Anaesthesia -  Paul Flecknell

Laboratory Animal Anaesthesia (eBook)

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2009 | 3. Auflage
304 Seiten
Elsevier Science (Verlag)
978-0-08-091899-0 (ISBN)
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109,65 inkl. MwSt
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Laboratory Animal Anesthesia looks at recent significant developments in anesthetic practices in laboratory experiments involving animals. It also provides information about basic standards for proper use of anesthesia. In addition, it examines the equipment and different anesthetic agents that are used in performing an experiment on animals. The book also discusses the profound effects of anesthesia on the physiological aspect of the animals' body systems, such as hypothermia and respiratory depression. The book addresses the proper management and care that should be provided for the animals that undergo anesthesia. Furthermore, it covers different anesthetic procedures that should be used on various kinds of small animals intended for laboratory experiments. The main goal of this book is to provide information about the different anesthetic agents used in experiments, and the proper standards to follow when using anesthetics on lab animals.• New edition provides new information on anesthesia and analgesia, and has an extensively revised and updated bibliography• Provides a balanced consideration of the needs of scientific research and the welfare of laboratory animals• Written by a veterinary anesthetist and scientist with over 30 years' experience in the field, and who is actively engaged in research in this area• Provides rapid, easily accessed information using tabulated summaries• Provides those with limited experience of anesthesia with the information they need to carry our procedures effectively, safely, and humanely• Provides sufficient depth for the more experienced anesthetist moving to this field

Paul Flecknell is a veterinarian with over 35 years of experience working with laboratory animals. He is a Diplomate of the European Colleges of Veterinary Anaesthesia and Analgesia and Laboratory Animal Medicine and an honorary Diplomate of the American College of Laboratory Animal Medicine. He has PhD in physiology, and is currently Professor of Laboratory Animal Science in the Institute of Neuroscience at Newcastle University. His main research interests are anaesthesia and analgesia of all species of animals and in particular the development of methods of pain assessment. He is the head of the Pain and Animal Welfare Science (PAWS) group at Newcastle. The group's current research work is focussed on novel methods of 'cage-side” assessment of pain, particularly using 'pain faces” and developing methods of measurement of affective state in rodents.
Laboratory Animal Anesthesia looks at recent significant developments in anesthetic practices in laboratory experiments involving animals. It also provides information about basic standards for proper use of anesthesia. In addition, it examines the equipment and different anesthetic agents that are used in performing an experiment on animals. The book also discusses the profound effects of anesthesia on the physiological aspect of the animals' body systems, such as hypothermia and respiratory depression. The book addresses the proper management and care that should be provided for the animals that undergo anesthesia. Furthermore, it covers different anesthetic procedures that should be used on various kinds of small animals intended for laboratory experiments. The main goal of this book is to provide information about the different anesthetic agents used in experiments, and the proper standards to follow when using anesthetics on lab animals.* New edition provides new information on anesthesia and analgesia, and has an extensively revised and updated bibliography* Provides a balanced consideration of the needs of scientific research and the welfare of laboratory animals* Written by a veterinary anesthetist and scientist with over 30 years' experience in the field, and who is actively engaged in research in this area* Provides rapid, easily accessed information using tabulated summaries* Provides those with limited experience of anesthesia with the information they need to carry our procedures effectively, safely, and humanely* Provides sufficient depth for the more experienced anesthetist moving to this field

Front Cover 1
Laboratory Animal Anaesthesia 4
Copyright Page 5
Contents 6
Preface 8
Preface to the Second Edition 10
Preface to the First Edition 12
Glossary 14
A 14
B 14
C 14
D 14
E 14
H 14
I 15
L 15
M 15
N 15
P 15
T 15
List of Tables 16
List of Figures 20
Acknowledgements 22
Introduction 24
Chapter 1 Preparing for Anaesthesia 26
Anaesthetic equipment and anaesthetic drugs 26
Other equipment 33
Personnel 39
The animal 40
Chapter 2 Anaesthesia 44
General anaesthesia 45
Chapter 3 Anaesthetic Management 104
Pre-operative preparations 104
Monitoring anaesthesia 106
Anaesthetic problems and emergencies 120
Chapter 4 Special Techniques 134
Use of neuromuscular blocking agents 134
Controlled ventilation 138
Long-term anaesthesia 144
Anaesthesia of pregnant animals 156
Anaesthesia of neonates 159
Anaesthesia for imaging 160
Chapter 5 Analgesia and Post-operative Care 164
The recovery room environment 165
Problems during the recovery period 167
Management of post-operative pain 172
Pain assessment 178
Pain relief 185
Conclusions 204
Chapter 6 Anaesthesia of Common Laboratory Species: Special Considerations 206
Small rodents 208
Rabbits 229
Cats 237
Dogs 242
Ferrets 246
Pigs 247
Sheep and goats 252
Primates 256
Other species 259
Bibliography 268
Appendix 1 Recommended Techniques and Physiological Data 300
Appendix 2 Estimation of Required Quantities of Volatile Anaesthetics and Anaesthetic Gases 306
Appendix 3 Examples of Dilutions of Anaesthetic Mixtures for Small Rodents 308
Appendix 4 Manufacturers of Equipment and Other Items Illustrated or Cited in the Text 312
Index 316
A 316
B 317
C 317
D 318
E 318
F 318
G 319
H 319
I 319
K 320
L 321
M 321
N 322
O 322
P 322
R 324
S 324
T 324
U 325
V 325
W 325
X 325
Y 325

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