Mycobacterium Bovis Infection in Animals and Humans

Charles O. Thoen, DVM, PhD is Professor of the Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University. Dr. Thoen is former Chairman of the Department of Veterinary Microbiology and Preventative Medicine at Iowa State University's College of Veterinary Medicine, Chairman of the International Union Against Tuberculosis and Lung Disease Scientific Committee on Tuberculosis in Animals, and former Chairman of the World Health Organization Committee on Animal Tuberculosis. James H. Steele DVM, MPH, is Professor Emeritus, Environmental Health, The University of Texas-Houston, School of Public Health, Center for Infectious Diseases, Houston, TX. Dr. Steele was formerly Chief Veterinary Officer, Assistant Surgeon General, U. S. Public Health Service; Consult to United Nations agencies, World Health Organization, Food and Agriculture Organization, Pan American Health Organization, International Atomic Energy Organization, and World Bank. Michael J. Gilsdorf is Director at National Center for Animal Health Programs - Eradication and Surveillance, USDA, APHIS, VS, Riverdale, Maryland.

Contributors. Preface. 1 Introduction. 2 Public Health Significance of M. Bovis. 3 Human TB due to M. bovis in Latin America and the Carribean. 4 Pathogenesis. 5 Epidemiology. 6 Diagnosis Tests for Bovine Tuberculosis. 7 Molecular Techniques: Applications in Epidemiologic Studies. 8 PCR Detection of M. Tuberculosis Complex in Formalin Fixed Tissues. 9 Economics of Bovine Tuberculosis. 10 A Tuberculosis Outbreak in Farmed Deer in Sweden and its Economic Consequences. 11 Benefit and Cost Assessment of the U. S. Bovine Tuberculosis Eradication Program. 12 The Fall and Rise of Bovine Tuberculosis in Great Britain. 13 Economic Significance of Bovine Tuberculosis in Italy and Impact of Mycobacterium Bovis Infection in Wild Swine. 14 The Impact of Wildlife Reservoirs on M. bovis on Programs for the Eradication of Tuberculosis in Cattle in Ireland. 15 Control and Eradication of Bovine Tuberculosis in Central Europe. 16 Bovine Tuberculosis in Latin American and the Carribean. 17 The Status of Mycobacterium Bovis in India. 18 Bovine Tuberculosis in Russia and the Former States of the Soviet Union. 19 Mycobacterium Bovis in Africa. 20 Current Challenges and Impacts to the U.S. National Bovine Tuberculosis Eradication Program. 21 Impact of Bovine Tuberculosis in Wildlife on a National Eradication Program (Canada). 22 The Bovine Tuerculosis Program in South Africa. 23 Bovine Tuberculosis in China. 24 Mycobacterium Bovis infections in Cattles in Germany. 25 Tuberculosis in Captive Wild Animals. 26 Tuberculosis in Fur Seals and Sea Lions Caused by Mycobacterium pinnipedii. 27 Tuberculosis in Non-human Primates. 28 DNA Vaccines Against Tuberculosis. 29 Bovine Tuberculosis: Environmental Public Health Preparedness Considerations for the Future. Index