Veterinary Hematology and Clinical Chemistry

Mary Anna Thrall , DVM, MS, DACVP, is a Professor and Section Chief, Department of Pathobiology at Ross University School of Veterinary Medicine in Basseterre, St. Kitts, West Indies.

Glade Weiser , DVM, DACVP, is a Professor, Special Appointment, in the Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine & Biomedical Sciences at Colorado State University in Fort Collins, Colorado.

Robin W. Allison , DVM, PhD, Dipl ACVP, is an Associate Professor in the Department of Veterinary Pathobiology, Center for Veterinary Health Sciences at Oklahoma State University in Stillwater, Oklahoma.

Terry W. Campbell , DVM, PhD is a Professor in the Department of Clinical Sciences at Colorado State University in Fort Collins, Colorado.

Contributors, ix

Preface, x

Preface to the First Edition, xii

Section I General Principles of Laboratory Testing and Diagnosis, 1

1 Laboratory Technology for Veterinary Medicine, 3
Glade Weiser

2 Sample Collection, Processing, and Analysis of Laboratory Service Options, 34
Glade Weiser

3 Perspectives in Laboratory Data Interpretation and Disease Diagnosis, 40
Glade Weiser and Robin W. Allison

4 Immunodiagnostics: Current Use and Future Trends in Veterinary Medicine, 51
Wayne A. Jensen

Section II Hematology of Common Domestic Species, 59

5 Erythrocyte Morphology, 61
Mary Anna Thrall

6 Classification of and Diagnostic Approach to Anemia, 75
Mary Anna Thrall

7 Nonregenerative Anemia, 81
Mary Anna Thrall

8 Regenerative Anemia, 87
Mary Anna Thrall

9 Classification of and Diagnostic Approach to Polycythemia, 114
Mary Anna Thrall

10 Introduction to Leukocytes and the Leukogram, 118
Glade Weiser

11 Neutrophil Production, Trafficking, and Kinetics, 123
Glade Weiser

12 Interpretation of Leukocyte Responses in Disease, 127
Glade Weiser

13 Molecular Diagnostics of Hematologic Malignancies, 140
Anne Avery

14 Laboratory Evaluation of Bone Marrow, 150
Mary Anna Thrall and Glade Weiser

15 Lymphoproliferative Disorders and Myeloid Neoplasms, 166
Mary Anna Thrall

16 Diagnosis of Disorders of Hemostasis, 185
Dale C. Baker

17 Principles of Blood Transfusion and Crossmatching, 205
Diane Brown and Linda M. Vap

Section III Hematology of Common Nondomestic Mammals, Birds, Reptiles, Fish, and Amphibians, 223

18 Mammalian Hematology: Laboratory Animals and Miscellaneous Species, 225
Terry W. Campbell

19 Hematology of Birds, 238
Terry W. Campbell

20 Hematology of Reptiles, 277
Terry W. Campbell

21 Hematology of Fish, 298
Terry W. Campbell

22 Hematology of Amphibians, 313
Terry W. Campbell

Section IV Clinical Chemistry of Common Domestic Species, 321

23 Laboratory Evaluation and Interpretation of the Urinary System, 323
Donald Meuten

24 Laboratory Evaluation of Electrolytes, 378
Andrea A. Bohn

25 Laboratory Evaluation of Acid-Base Disorders, 393
Glade Weiser

26 Laboratory Evaluation of the Liver, 401
Robin W. Allison

27 Laboratory Evaluation of the Pancreas and Glucose Metabolism, 425
Robin W. Allison

28 Laboratory Evaluation of Digestion and Intestinal Absorption, 441
Dawn Seddon

29 Laboratory Evaluation of Plasma and Serum Proteins, 460
Robin W. Allison

30 Laboratory Detection of Muscle Injury, 476
Robin W. Allison

31 Laboratory Evaluation of Lipids, 480
M. Judith Radin

32 Laboratory Evaluation of the Thyroid, Adrenal, and Pituitary Glands, 497
Donald Meuten

33 Parathyroid Glands and Calcium and Phosphorus Metabolic Pathology, 545
Donald Meuten

Section V Clinical Chemistry of Common Nondomestic Mammals, Birds, Reptiles, Fish, and Amphibians, 569

34 Chemical Chemistry of Mammals: Laboratory Animals and Miscellaneous Species, 571
Terry W. Campbell

35 Clinical Chemistry of Birds, 582
Terry W. Campbell

36 Clinical Chemistry of Reptiles, 599
Terry W. Campbell

37 Clinical Chemistry of Fish and Amphibians, 607
Terry W. Campbell

Section VI Clinical Case Presentations, 615

This section includes 74 cases with clinicopathologic data accompanied by an interpretive discussion and diagnostic summary.

Index, 750

Extra PowerPoint presentations available online at www.wiley.com/go/thrall.

"It's a powerful reference packed with practical applications and should be considered a 'must' for any veterinary reference library." (The Bookwatch, 1 November 2012)