Blick ins Buch

Satellite DNAs in Physiology and Evolution (eBook)

eBook Download: PDF

2021 | 1st ed. 2021
XII, 234 Seiten
Springer International Publishing (Verlag)
978-3-030-74889-0 (ISBN)

Lese- und Medienproben

Ebook-Leseprobe (PDF)

This book gives a comprehensive overview of the unique roles that non-coding repetitive elements such as satellite DNAs play in different physiological and evolutionary processes.

It presents the gene-regulatory aspect of satellite DNAs in different model systems including mammals, insects and plants. In addition, evolutionary aspects of activation of satellite DNAs in terms of transcription and proliferation are highlighted, revealing the role of satellite DNAs in the process of adaptation to changing environment and in the speciation process.

Finally, the book discusses satellite DNA activation during pathological transformation and the mechanisms by which they affect disease progression. Namely, some satellite DNAs promote the oncogenic processes by affecting genome epigenetic regulation as well as genome integrity. Readers get a full overview of the latest research on satellite DNA.

Ðurdica Ugarkovic received her PhD in Biochemistry at University of Zagreb and performed postdoctoral studies at the Laboratory of Applied Molecular Biology, Johannes Gutenberg University Mainz, Germany. She is senior researcher and head of Laboratory of Evolutionary Genetics at Ruder Boškovic Institute in Zagreb and professor at Josip Juraj Strossmayer University of Osijek, Croatia.

Her major research interest is studying evolution and function of satellite DNA, which is a major DNA component of heterochromatin in many eukaryotes. Using the beetle Tribolium castaneum as a model system, her group demonstrated for the first time the role of satellite DNA in the modulation of gene expression and revealed the molecular mechanism of their gene-regulatory activity. The influence of satellite DNA on neighbouring genes is epigenetic in nature and is induced upon heat stress, suggesting an important role of satellite DNA in the environmental adaptation. Ð. Ugarkovic predicted the presence of functional elements within satellite DNAs and, together with colleagues at the Ruder Boškovic Institute, provided the first experimental evidence for the existence of a set or a 'library' of satellite DNAs shared among related species. This explained a mode of satellite DNA evolution which is based on random amplification from the common 'library'.

She is member of the European Molecular Biology Organization (EMBO) since 2000 and associate member of the Croatian Academy of Sciences and Arts.

Erscheint lt. Verlag	13.8.2021
Reihe/Serie	Progress in Molecular and Subcellular Biology
Reihe/Serie	Progress in Molecular and Subcellular Biology
Zusatzinfo	XII, 234 p. 34 illus., 29 illus. in color.
Sprache	englisch
Themenwelt	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
	Naturwissenschaften ► Chemie
	Technik ► Maschinenbau
Schlagworte	Centromeric Repeats • Gene expression regulation • Genome Evolution • genome organization • Heterochromatin • Meioic Drive • Mobile elements • Non-coding DNA • Repeatome • repetitive DNA • SatDNA • satellite DNA • Satellite DNA Transcription • Satellitome • tandem repeats
ISBN-10	3-030-74889-8 / 3030748898
ISBN-13	978-3-030-74889-0 / 9783030748890

Informationen gemäß Produktsicherheitsverordnung (GPSR)
Haben Sie eine Frage zum Produkt?

PDF (Wasserzeichen)
Größe: 5,6 MB

DRM: Digitales Wasserzeichen
Dieses eBook enthält ein digitales Wasserzeichen und ist damit für Sie personalisiert. Bei einer missbräuchlichen Weitergabe des eBooks an Dritte ist eine Rückverfolgung an die Quelle möglich.

Dateiformat: PDF (Portable Document Format)
Mit einem festen Seitenlayout eignet sich die PDF besonders für Fachbücher mit Spalten, Tabellen und Abbildungen. Eine PDF kann auf fast allen Geräten angezeigt werden, ist aber für kleine Displays (Smartphone, eReader) nur eingeschränkt geeignet.

Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.

Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.

Print-Ausgabe

Buch | Hardcover

192,59 €