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In Situ Hybridization

Principles and Practice
Buch | Hardcover
260 Seiten
1990
Oxford University Press (Verlag)
978-0-19-261906-8 (ISBN)
37,40 inkl. MwSt
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"In situ" hybridization is a technique of molecular biology used to identify genes encoding for particular proteins, by the use of complimentary strands of genetic material (DNA or RNA). It is useful in the study of cellular function and disease.
"In situ" hybridization is a technique of molecular biology that is used to localize the genetic machinery (genes) involved in protein production, by the use of complimentary strands of genetic material (oligonucleotides of DNA or RNA). It is important in the study of the mechanisms underlying cellular function and disease. This book covers all aspects of "in situ" hybridization, from the basic principles of molecular biology, through the various methodological advances, to its most up-to-date applications in pathology.

Basic background of molecular biology, V.T-W.Chan et al; principles of "in situ" hybridization, H.Hofler; radioactive labels - autoradiography and choice of emulsions for "in situ" hybridization, M.A.W.Brady and M.A.Finlan; non-radioactive probes - preparation, characterization, and detection, V.T-W.Chan and J.O'D.McGee; oligonucleotide probes for "in situ" hybridization, R.Lathe; principles and applications of complementary RNA probes, S.J.Gibson and J.M.Polak; quantification of radioactive "in situ" hybridization signals, A.P.Davenport and D.J.Nunez; "in situ" hybridization and the study of development, D.G.Wilkinson; "in situ" hybridization in virology, C.G.Teo; chromosomal assignment of genes, B.Bhatt and J.O'D.McGee; interphase cytogenetics of solid tumours, A.H.N.Hopman et al; single and simultaneous nucleic acid detection in archival human biopsies - application of non-isotopic "in situ' hybridization and the polymerase chain reaction to the analysis of human and viral genes, C.S.Herrington et al; photomicrography, S.Bradbury.

Erscheint lt. Verlag 30.4.1990
Reihe/Serie Modern Methods in Pathology S.
Zusatzinfo halftones and line drawings throughout, bibliography
Verlagsort Oxford
Sprache englisch
Maße 160 x 230 mm
Gewicht 610 g
Themenwelt Naturwissenschaften Biologie Genetik / Molekularbiologie
Naturwissenschaften Biologie Zellbiologie
Technik Umwelttechnik / Biotechnologie
ISBN-10 0-19-261906-3 / 0192619063
ISBN-13 978-0-19-261906-8 / 9780192619068
Zustand Neuware
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