Chromatin and Gene Regulation (eBook)

Bryan M. Turner is Professor of Experimental Genetics at School of Cancer Sciences, Institute of Biomedical Research, University of Birmingham in Birmingham, UK. He was educated at University College London, where he earned his BSc in Biochemistry and PhD in Human Biochemical Genetics.

Prologue.

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1. Controlling transcription: shared aims and common
mechanisms.

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2. Transcription in eukaryotes: the problems of complexity.

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3. The nucleosome: chromatin's structural unit.

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4. Histone tails: modifications and epigenetic information.

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5. Higher-order chromatin structures and nuclear
organisation.

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6. Transcription in a chromatin environment.

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7. How the transcription machinery deals with chromatin.

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8. Chromatin remodelling machines.

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9. Heterochromatin.

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10. Long-term silencing of gene expression.

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11. Cellular memory and imprinting.

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12. Mechanisms of dosage compensation

"In conclusion, and to get back to the culinary metaphor (which
rang a chord with me as a French reader), it seems that reading
this book could be likened to a good appetizer - it should
stimulate students to be curious about the rest of the meal and,
therefore, run off and read up on the individual aspects of the
story." Genevieve Almouzni, Journal of Cell Science, June
2002

"...probably the most informative, carefully thought-out and
well-written book on the subject ... invaluable not only to the
undergraduate and postgraduate level students for whom it is
written, but also for the chromatin community at large. In a
fast-growing and ever-expanding field such as the field of
chromatin research, such a book will be a rich source of reference
for years to come." J Zlatanova, Heredity (2002) 89,
401

"Chromatin and Gene Regulation offers a concise yet
intellectually critical introduction to ... gene regulation."
Science, April 2003

"[The] gentle progression through the many levels of gene
regulation makes this difficult subject easy to understand. The
book can easily be read cover to cover, while the clear chapter
layout allows students to dip in at any point. This book is ideal
for students and researchers wishing to learn more about this
rapidly developing subject." Lindsay Emerson, University of
Essex, Newsletter of the British Society for Cell Biology, Summer
2003