Quantitative Imaging Tools for Lung Cancer Drug Assessment

Preface (Thomas M. Baer and James L. Mulshine). Chapter 1: Incorporating Imaging into Drug Development: An Industry Perspective (Philip S. Murphy and Debasish Roychowdhury). Chapter 2: Developing Imaging Tools for Drug Development: Critical Technology, Clinical Data and Regulatory (Rafal Dziadziuszko, Fred R. Hirsch and Paul A. Bunn, Jr). Chapter 3: Quantitative Imaging in CT Lung Cancer Drug Development and Evaluation (Ricardo S. Avila). Chapter 4: Volumetric CT Imaging for Response Assessment in Lung Cancer: A Platform for Translational Research (Binsheng Zhao and Lawrence H. Scwhartz). Chapter 5: Emerging Radiological Software Standards and Development Technologies: Impact on Clinical Translation and Trials (John Pearson, Lawrence Tarbox, Gianluca Paladini, John G. Wolodzko, Paula M. Jacobs, and Zhenghong Lee). Chapter 6: Statistical Considerations Underlying Therapeutic Response Criteria for Lung Cancer: A Review in the Context of Emergence of Multi-Slice CT Scanner and Computer Assisted Diagnostic Algorithm for Volumetric Assessment (Madhu Mazumdar and Xi Kathy Zhou). Chapter 7: Programs Supporting Quantitative Imaging in Biomedicine at the National Institute for Standards and Technology (Thomas M. Baer and Charles W. Clark). Appendix A: Evolving Imaging Resources: Public Access Databases (Laurence Clarke). Appendix B: Biomedical Imaging Archive Network (Thomas M. Baer and James L. Mulshine). Appendix C: Developing CT Image-Processing Tools to Accelerate Progress in Lung Cancer Drug Development (James L. Mulshine, Ricardo S. Avila, Fred R. Hirsch, and David Yankelevitz).