Enantioselective Synthesis of Beta-Amino Acids (eBook)

Covers all facets of the synthesis of ß-amino acids

As evidenced by an exponential increase in the literature published
on the subject, interest in ß-amino acids has grown over the
past several years. With major pharmaceutical applications, these
amino acids are now studied across multiple lines of research,
including combinatorial chemistry, medicinal chemistry, molecular
design, proteomics, and others.

This Second Edition of Enantioselective Synthesis of ß-Amino
Acids updates reviews included in the First Edition while also
covering new developments since its publication. The book presents
detailed discussions of the most important methods for the
synthesis of ß-amino acids. In most cases, the lead chemist
who originally developed a method provides an authoritative
description of it.

In addition, Enantioselective Synthesis of ß-Amino Acids,
Second Edition:

* Features introductory overviews on the structural types of
relevant ß-amino acid targets and salient ß-amino acids
present in natural products

* Dedicates several chapters to advances in the synthesis of
oligomers from ß-amino acids

* Includes general and practical procedures for the preparation of
ß-amino acids in each chapter

* Discusses the most important methods that have been recently
developed for the asymmetric synthesis of cyclic and open-chain
ß-amino acids

* Includes a report on the preparation of libraries of enantiopure
ß-amino acids using combinatorial approaches

The only book of its kind available today, Enantioselective
Synthesis of ß-Amino Acids, Second Edition offers upper-level
students and professionals an essential resource for pharmaceutical
development, medicinal chemistry, and biochemistry.