Functional Synthetic Receptors (eBook)

Thomas Schrader is Professor of Organic Chemistry at the University of Marburg. He studied chemistry and obtained his PhD in 1988 under W. Steglich at the Friedrich-Wilhelms-University of Bonn. After a postdoctorate stay at Princeton University under E.C. Taylor on total synthesis of antitumor agents, he gained his lecturing qualification at the University of Düsseldorf. In 2000 he joined the University of Marburg as associate professor. His research focuses on bioorganic aspects of supramolecular systems, optimizing and multiplying new binding motifs for characteristic structural features in biomolecules - a concept that leads to artificial receptor molecules capable of specifically interfering with biological processes. Applications include biosensors, drugs countering protein misfolding and tweezers for protein assembly. Professor Schrader is the holder of the Bredereck-symposium prize in bioorganic chemistry (2001). Andrew D. Hamilton received his PhD from Cambridge University in 1980, and the following year carried out his postdoc research at Université Louis Pasteur, Strasbourg. Between 1981 and 1988 he was Assistant Professor for Chemistry at Princeton University, thereafter Associate Professor until 1992, when he became Full Professor at the University of Pittsburgh, a post he held until 1997. Since 1997 he has been Irénée duPont Professor of Chemistry and, since 1998, Professor of Molecular Biophysics and Biochemistry at Yale University. Here he held the Chair of the Chemistry Department between 1999 and 2003, and has been Deputy Provost for Science and Technology since 2003. Professor Hamilton lectures at several universities in the USA.

Amino Acid, Peptid and Protein Receptors
Carbohydrate Receptors
Ammonium, Amidinium and Guanidinium Receptors
Anion Receptors
Molecular Capsules and Self Assembly
Dynamic Combinatorial Libraries based on Molecular Recognition
Molecular Machines
Self-Replication
Artificial (Pseudo)peptides for Molecular Recognition and Catalysis
Carbohydrate Receptors
Ammonium, Amidinium, Guanidinium, and Pyridinium Cations
Artificial Pyrrole-based Anion Receptors
Molecular Containers in Action
Formation and Recognition Properties of Dynamic Combinatorial Libraries
Synthetic Molecular Machines
Towards Self-replicating Nanorobots - A Chemical Perspective