The Future of Aging (eBook)

Part 1: Introduction and Orientation;

Chapter 1 Bridges to Life; Ray Kurzweil, Kurzweil Technologies, Inc. Wellesley, MA, and Terry Grossman, M.D., Frontier Medical Institute, Denver, CO;
Chapter 2 Analyzing Predictions: An Anthropological View of Anti-Aging Futures; Courtney Everts Mykytyn, Ph.D., Department of Anthropology, University of Southern California, Los Angeles, CA, USA;
Chapter 3 Towards Naturalistic Transcendence: The Value of Life and Life Extension to Persons as Conative Processes; Steven Horrobin, Ph.D., College of Medicine, University of Edinburgh, Scotland, UK;
Chapter 4 The Ethical Basis for Using Human Embryonic Stem Cells in the Treatment of Aging; L. Stephen Coles, M.D., Ph.D., David Geffen School of Medicine, UCLA, Los Angeles, CA, USA;
Chapter 5 Evolutionary Origins of Aging, Joshua Mitteldorf, Ph.D., Dept of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ
Chapter 6 Precedents for the Biological Control of Aging: Experimental Postponement, Prevention, and Reversal of Aging Processes; Gregory M. Fahy, Ph.D., Intervene Biomedical, Norco, CA, USA;

Part 2: The Future of Aging
Chapter 7 An Approach to Extending Healthspan and Lifespan Today; Chris Heward, Ph.D.*, President, Kronos Science Laboratory, Phoenix, AZ, USA; *Deceased
Chapter 8 Near-Term Prospects for Amelioration of Cardiovascular Aging, Roger Yu, M.D., Beth Israel Deaconess Medical Center, Boston, MA 02215, and Mohammad Navab, Ph.D., David Geffen School of Medicine, UCLA, Los Angeles, CA, USA ;
Chapter 9 Near Term Prospects for Broad Spectrum Amelioration of Cancer; Zheng Cui, Ph.D., Wake Forest University School of Medicine, inston-Salem, NC, USA;
Chapter 10 Small Molecule Modulators of Sirtuin Activity; Francisco J. Alcain, Ph.D., Robin K. Minor, Ph.D., Jose M. Villalba, Ph.D., Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, Córdoba, Spain, and Rafael de Cabo, Ph.D.,Laboratory of Experimental Gerontology, National Institute on Aging, NIH, Baltimore, MD, USA;
Chapter 11 Evolutionary Nutrigenomics; Michael Rose, Ph.D., Anthony D. Long, Ph.D., Laurence D. Mueller, Ph.D.,Cristina L. Rizza, Ph.D., Kennedy C. Matsagas, Ph.D.,Lee F. Greer, Ph.D., and Bryant Villeponteau, Ph.D.Genescient, LLC, Irvine, CA, USA;
Chapter 12 Biological Effects of Calorie Restriction:Implications for Modification of Human Aging; Stephen R. Spindler, Ph.D., Department of Biochemistry,University of California at Riverside, Riverside, CA, USA;
Chapter 13 Calibrating Notch/TGF-ß Signaling for Youthful, Healthy Tissue Maintenance and Repair; Morgan E. Carlson, Ph.D. and Irina M. Conboy, Ph.D., Department of Bioengineering, University of California, Berkeley, CA, USA;
Chapter 14 Embryonic Stem Cells:Prospects of Regenerative Medicinefor the Treatment of Human Aging; Mike West, Ph.D., Chief Scientific Officer, BioTime, Inc., and Embryome Sciences, Inc., Alameda, CA, USA, and Adjunct Professor, University of California at Berkeley, Berkeley, CA, USA
Chapter 15 Maintenance and Restoration of Immune System Function; Richard Aspinall, Ph.D., and Wayne Mitchell, Ph.D., School of Medicine, Division of Investigative Science,Imperial College London, London, UK
Chapter 16 Mitochondrial Manipulation as a Treatment for Aging; Rafal Smigrodzki, M.D., and Francisco R. Portell, B.S., Gencia, Inc., Charlottesville, VA, USA;
Chapter 17 Life Extension by Tissue and Organ Replacement; Anthony Atala, M.D., Director, Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA;
Chapter 18 Telomeres and the Arithmetic of Human Longevity; Abraham Aviv, M.D., and John D. Bogden, Ph.D., The Center of Human Development and Aging, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ, USA;
Chapter 19 Repairing Extracellular Aging and Glycation; John Furber, C.E.O.,