Apoptosis, Cell Signaling, and Human Diseases (eBook)
XVI, 402 Seiten
Humana Press (Verlag)
978-1-59745-199-4 (ISBN)
Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volumes 1 and 2, present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways. Particular attention is given to apoptosis in human diseases, such as different forms of cancer. These comprehensive volumes integrate the most innovative and current findings. The contributors are at the forefront of scientific discovery.
(for both volumes)Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volumes 1 & 2, present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways. Particular attention is given to apoptosis in human diseases, such as different forms of cancer and neurodegenerative diseases. These comprehensive volumes integrate the most innovative and current findings from several related disciplines of scientific research, including pathology, genetics, virology, cell biology, immunology, and molecular biology. Volume 1 is divided into two sections: "e;Malignant Transformation and Metastasis"e; and "e;Molecular Basis of Disease Therapy."e; Volume 2 follows a similar structure and is divided into sections entitled "e;Kinases and Phosphate"e; and "e;Molecular Basis of Cell Death."e; All of the contributors are at the forefront of scientific discovery, and the reviews they present systemically examine the most exciting and innovative aspects of their particular areas of expertise. Researchers will find these volumes of major benefit as they search for novel and more effective treatments for human diseases.
Section I. Kinases and Phosphatases
Significance of Protein Kinase A in Cancer
Maria V. Nesterova and Y. S. Cho-Chung
Protein Kinase C and Cancer
Mary E. Reyland
The Role of PI3K-Akt Signal Transduction in Virus Infection
Samantha Cooray
Cyclin-Dependent Kinase 5: A Target for Neuroprotection?
Frank Gillardon
Critical Roles of the Raf/MEK/ERK Pathway in Apoptosis and Drug Resistance
James A. McCubrey, Fred E. Bertrand, Linda S. Steelman, Fumin Chang, David M. Terrian, and Richard A. Franklin
MAP Kinases Signaling in Human Diseases
Philippe Roux and J.Blenis
Serine/Threonine Protein Phosphates in Apoptosis
Gro Gausdal, Camilla Krakstad, Lars Herfindal, and Stein Ove Doskeland
Urokinase/Urokinase Receptor-Mediated Signaling in Cancer
Sreerama Shetty, and Steven Idell
Section II. Molecular Basis of Cell Death
Signaling Pathways That Protect the Heart Against Apoptosis Induced by Ischemia and Reperfusion
Zheqing Cai and Gregg L. Semenza
Cyclooxygenase-2 Gene Expression: Transcriptional and Posttranscriptional Controls in Intestinal Tumorigenesis
Shrikant Anant and Sripathi M. Sureban
Death Receptors: Mechanisms, Biology and Therapeutic Potential
Sharmila Shankar and Rakesh Srivastava
DNA Damage-Dependent Apoptosis
Tomasz Skorski
The Role of Proteasome in Apoptosis
Peter Low
Apoptosis Induction in T Lymphocytes by HIV
Maria Saveria Gilardini Montani
Inhibitors of Apoptosis Proteins and Caspases
Jai Yu, John Silke and Paul G. Ekert
Intracellular Pathways Involved in DNA-Damage and Repair to Neuronal Apoptosis
Maurizio Memo
The Biology of Caspases
Tasman James Daish and Sharad Kumar
| Erscheint lt. Verlag | 5.11.2007 |
|---|---|
| Zusatzinfo | XVI, 402 p. 49 illus., 1 illus. in color. |
| Verlagsort | Totowa |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Allgemeines / Lexika |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie | |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
| Naturwissenschaften ► Biologie ► Zellbiologie | |
| Technik | |
| Schlagworte | DNA • gene expression • genes • HIV • Infection • Infectious Diseases • Molecular Biology • Molecular mechanisms • signal transduction • Virus |
| ISBN-10 | 1-59745-199-1 / 1597451991 |
| ISBN-13 | 978-1-59745-199-4 / 9781597451994 |
| Haben Sie eine Frage zum Produkt? |
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