Modelling and Control in Biomedical Systems 2006 (eBook)

Cover 1
CONTENTS 8
PART I: KEYNOTE PAPERS 14
Chapter 1. Dynamic Modeling in Diabetes:From Whole Body to Genes 14
Chapter 2. LIDCO - From the laboratory to protocolized goal directed therapy 16
Chapter 3. Elastic scattering spectroscopy for noninvasive detection of cancer 18
Chapter 4. Clinical decision support in monitoring and information systems 20
PART II: OPTICAL METHODS FOR IN-VIVO DIAGNOSIS / CLINICAL DIAGNOSIS BY IMAGE PROCESSING 24
Chapter 5. Acousto-optic imaging techniques for optical diagnosis 24
Chapter 6. Improvement of the contrast in cancer detection by autofluorescence bronchoscopy using a narrow spectral violet excitation: a preliminary study 30
Chapter 7. Fuzzy clustering on abdominal MRI for adipose tissue quantification 36
Chapter 8. Retinal angiogram registration by estimation of distribution algorithm 42
Chapter 9. Automatic multimodal registration of gated cardiac PET, CT and MR sequences 48
Chapter 10. Diffuse reflectance spectroscopy Monte-Carlo Modeling: Elongated arterial tissues optical properties 54
Chapter 11. Three-dimensional coherent optical diffraction tomography of transparent living samples 60
Chapter 12. A portable raman probe for in vivo pathological tissues characterisation 66
PART III: IDENTIFICATION AND SIGNAL PROCESSING IN BIOMEDICAL SYSTEMS 70
Chapter 13. Analysis of double-tracer Glucose kinetics in humans during oral Glucose tolerance test 70
Chapter 14. Towards a reliable posture estimation for standing in Paraplegia 76
Chapter 15. Clinical cardiovascular identification with limited data and fast forward simulation 82
Chapter 16. Modelling of haemodialysis in limiting serum free light chains in patients with renal failure 88
Chapter 17. Extraction of reproducible epileptic patterns on scalp EEG 94
Chapter 18. Multiple strategies for parameter estimation via a hybrid method: a comparative study 100
Chapter 19. Multi-lead T wave end detection based on statistical hypothesis testing 106
Chapter 20. Structural identifiability of parallel pharmacokinetic experiments as constrained systems 112
Chapter 21. Separation of arterial pressure into solitary waves and windkessel flow 118
Chapter 22. Multi variable event detection in intensive care units 124
Chapter 23. Knowledge extraction about sleep/wake stages using data driven methods 130
Chapter 24. Isometric muscle contraction induced by repetitive peripheral magnetic stimulation 136
Chapter 25. Needle insertions modelling: identifiability and limitations 142
Chapter 26. Single black-box models for two-point non-invasive temperature prediction 148
Chapter 27. 3D heart motion estimation using endoscopic monocular vision system 154
Chapter 28. Investigation on biomedical measurement accuracy in electrode-skin tests 160
Chapter 29. Identification of regulatory pathways of the cell cycle in fission yeast 166
Chapter 30. Reduced model for forced expiration and analysis of its sensitivity 172
Chapter 31. A model of free fatty acid kinetics during intravenous glucose tolerance test 178
Chapter 32. Modelling the effects of the electrodes position on the surface EMG characteristics 184
Chapter 33. Multiparametric human liver fibrosis identification from ultrasound signals 190
Chapter 34. Human skin thermal properties identification by periodic method in the frequency domain 196
Chapter 35. Modelling and analysis of HRV under physical and mental workloads 202
Chapter 36. System identification of photosensitiser uptake kinetics in photodynamic therapy 208
Chapter 37. On the modeling of paraffin through Raman spectroscopy 214
Chapter 38. Insulin sensitivity index also accounting for insulin action dynamics: importance in diabetes 220
Chapter 39. Postural time-series analysis of elderly and control subjects using entropy 226
Chapter 40. A comparison between two fractional multimodels structures for rat muscles modelling 232
Chapter 41. Characteristic phase plane pattern of human postural sway 238
Chapter 42. The Glucose minimal model: population vs individual parameter estimation 244
PART IV: BIOMEDICAL FUNCTIONAL IMAGING 250
Chapter 43. Methods for improving reliability of GLLS for parametric image generation 250
Chapter 44. Medical image segmentation techniques for virtual endoscopy 256
Chapter 45. Fuzzy fusion system for brain MRI image segmentation 262
Chapter 46. Tumor segmentation from PET/CT images using level sets method 268
Chapter 47. A study of partial volume effects on clustering-aided parametric images 274
Chapter 48. Efficient and automatic abdominal image registration based on active contour 280
Chapter 49. A novel integrative bioinformatics environment for encoding and interrogating timelapse microscopy images 286
Chapter 50. Method for analysis of volume progression tissues in hemiplegic subject 292
Chapter 51. Ga-Backpropagation hybrid training and morphometric parameters to classify breast tumours on ultrasound images 298
Chapter 52. 2-D panoramas from cystoscopic image sequences and potential application to fluorescence imaging 304
Chapter 53. Parametric imaging of acetylcholinesterase activity with PET: evaluation of different methods 310
PART V: BIOMEDICAL SYSTEM CONTROL 316
Chapter 54. Bolus tracking using local density information 316
Chapter 55. Fuzzy advisor algorithm for Glucose regulation in type 1 diabetic patients on a multi-doses regime 322
Chapter 56. An FES-assisted gait training system for hemiplegic stroke patients based on inertial sensors 328
Chapter 57. Control architecture of a 3-DOF upper limbs rehabilitation robot 334
Chapter 58. Adaptive control of computed tomograph angiography 340
Chapter 59. Nonlinear control of HIV-1 infection with a singular perturbation model 346
Chapter 60. Insulin + Nutrition control for tight critical care glycaemic regulation 352
Chapter 61. Stochastic insulin sensitivity models for tight glycaemic control 358
Chapter 62. Strategies for haemodynamic control of extracorporeal circulation 364
Chapter 63. The benefits of using Guyton's model in hypotensive control system 370
Chapter 64. Kinematic trajectory generation in a neuromusculoskeletal model with somatosensory and vestibular feedback 376
Chapter 65. A nonlinear model for vasoconstriction 382
Chapter 66. Inertial gait phase detection: Polynomial nullspace approach 388
Chapter 67. A supervisor for volume-controlled tidal liquid ventilator using independent piston pumps 394
Chapter 68. A real-time predictive scheme for controlling hygrothermal conditions of neonate incubators 400
Chapter 69. Modelling and analysis physiological motor control using Bond graph 406
Chapter 70. Toward modelling the human sensory motor system 412
Chapter 71. Joint torques estimation in human standing based on a fuzzy descriptor unknown inputs observer 418
PART VI: MODELLING, PHYSIOLOGICAL SYSTEMS, BIOINFORMATICS AND HEALTH CARE 424
Chapter 72. A preliminary study on metabolism modelling with capillary 424
Chapter 73. Neuromuscular blockade advisory system randomised, controlled clinical trial: Preliminary results 430
Chapter 74. Deterministic modeling of Interferon-Beta signaling pathway 436
Chapter 75. Physiological modelling and analysis of the pulmonary microcirculaton in septic patients 442
Chapter 76. Modeling an enzymatic diffusion-reaction process in one dimensional space 448
Chapter 77. Garch models for drug effects on patient heart rate, during general anaesthesia 454
Chapter 78. Modelling drugs' pharmacodynamic interaction during general anaesthesia: the choice of pharmacokinetic model 460
Chapter 79. Cardiovascular system modelling of heart-lung interaction during mechanical ventilation 466
Chapter 80. A differential model of controlled cardiac pacemaker cell 472
Chapter 81. Modelling light and moderate exercise in type 1 diabetic patients with Glycogen depletion and replenishment 478
Chapter 82. A nonlinear mathematical model of an immunotherapy treatment of parathyroid carcinoma 484
Chapter 83. A PK-PD model of cell cycle response to topotecan 490
Chapter 84. Interpolated maps of biomechanical characteristics of human skull 496
Chapter 85. A continuously updated hybrid blood gas model for ventilated patients 502
Chapter 86. Analysis of rupture of intracranial saccular aneurysms 508
Chapter 87. Modeling and control of HIV dynamics 514
Chapter 88. In silico analysis of P53 response to DNA damage 520
Chapter 89.Model analysis of the choke points arrangement during forced expiration 526
Chapter 90. A fuzzy classifier for drug sensitivity in septic patients during cardiopulmonary bypass 532
Chapter 91. A model of the ventricular activity using Bond graphs 538
Chapter 92. Model of the knee for understanding the squat movement biomechanics 544
Chapter 93. Generic probabilistic networks in medical decision support 550
Chapter 94. Generalized cellular automata for studying the behavior of cell populations 556
Chapter 95.Patient Variability and Uncertainty Quantification in Anaesthesia: Part I – PKPD Modelling and Identification 562
Chapter 96. Patient Variability and Uncertainty Quantification in Anaesthesia: Part II – PKPD Uncertainty 568
Author Index 574