Current Topics in Developmental Biology (eBook)
175 Seiten
Elsevier Science (Verlag)
978-0-08-052466-5 (ISBN)
Reviews include:
* A role for endogenous electric fields in wound healing
* The role of mitotic checkpoint in maintaining genomic stability
* The regulation of oocyte maturation
* Stem cells: A promising source of pancreatic islets for transplantation in type 1 diabetes
* Differentiation potential of adipose derived adult stem (ASAS) cells
The exceptional reviews in this volume of Current Topics in Developmental Biology will be valuable to both clinical and fundamental researchers, as well as students and other professionals who want an introduction to current topics in cellular and molecular approaches to developmental biology and clinical problems of aberrant development.
* Series Editor Gerald Schatten is one of the leading minds in reproductive and developmental science
* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine
* The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
Together with other volumes in this series, Volume 58 presents thoughtful and forward-looking articles on developmental biology and developmental medicine. Reviews include:* A role for endogenous electric fields in wound healing* The role of mitotic checkpoint in maintaining genomic stability * The regulation of oocyte maturation* Stem cells: A promising source of pancreatic islets for transplantation in type 1 diabetes* Differentiation potential of adipose derived adult stem (ASAS) cellsThe exceptional reviews in this volume of Current Topics in Developmental Biology will be valuable to both clinical and fundamental researchers, as well as students and other professionals who want an introduction to current topics in cellular and molecular approaches to developmental biology and clinical problems of aberrant development.* Series Editor Gerald Schatten is one of the leading minds in reproductive and developmental science* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine* The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
Cover 1
Copyright Page 5
Contents 6
Contributors 10
Preface 12
Chapter 1. A Role for Endogenous Electric Fields in Wound Healing 14
I. Introduction 15
II. Endogenous Electric Fields Measured near Wounds 17
III. Epithelial Cells Exhibiting Galvanotaxis 20
IV. How Do Motile Cells Sense and Respond to the Imposed Electric Field? 24
V. Can Imposed Electric Fields be used to Stimulate Wound Healing? 27
VI. Clinical Trials Using Electric Fields to Stimulate Wound Healing 32
VII. Summary 33
References 34
Chapter 2. The Role of Mitotic Checkpoint in Maintaining Genomic Stability 40
I. Introduction 40
II. The Kinetochore is a Complex Structure for Cell Division 42
III. The Mitotic Checkpoint 44
IV. Mutations in Mitotic Checkpoint Proteins and Tumorigenesis 54
V. Conclusions and Future Directions 58
Acknowledgments 61
References 61
Chapter 3. The Regulation of Oocyte Maturation 66
I. Concept of Oocyte Maturation 67
II. Life and Death of an Oocyte 69
III. Maturation Promoting Factor 83
IV. Initiation of Oocyte Maturation 86
V. Cytoplasmic Control of Maturation 97
VI. Concluding Remarks 111
Acknowledgments 112
References 112
Chapter 4. Stem Cells: A Promising Source of Pancreatic Islets for Transplantation in Type 1 Diabetes 124
I. Introduction 125
II. Islet Transplantation: Success with Limitations 126
III. Alternative Sources of Transplantable Islets 127
IV. Differentiation of Embryonic Stem Cells into Insulin-producing Cells 128
V. Identification of the Elusive Pancreatic Stem Cell 132
VI. Existence of Nonpancreatic Islet Progenitor Cells 139
VII. Summary 141
References 142
Chapter 5. Differentiation Potential of Adipose Derived Adult Stem (ADAS) Cells 150
I. Introduction 150
II. Adipose Tissue„Physiology 151
III. Adipose Tissue„Pathology 155
IV. Adipose Derived Adult Stem (ADAS) 157
V. ADAS Cell Differentiation Potential and Potential Therapeutic Applications 159
VI. Functional Tissue Engineering Considerations 164
VII. Conclusions and Future Directions 166
Acknowledgments 166
References 167
Index 174
Contents of Previous Volumes 180
Color Plate Section 190
| Erscheint lt. Verlag | 18.12.2003 |
|---|---|
| Sprache | englisch |
| Themenwelt | Sachbuch/Ratgeber |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| Naturwissenschaften ► Biologie ► Zellbiologie | |
| Technik | |
| ISBN-10 | 0-08-052466-4 / 0080524664 |
| ISBN-13 | 978-0-08-052466-5 / 9780080524665 |
| Haben Sie eine Frage zum Produkt? |
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