Advances in Virus Research (eBook)

Cover Page 1
Contents 6
Chapter 1: Spread of Plant Virus Disease to New Plantings: A Case Study of Rice Tungro Disease 9
I. Introduction 10
II. Rice Tungro Disease 15
III. Area-Wide Investigation of Rice Tungro Disease Incidence 19
Acknowledgments 34
References 35
Chapter 2: In A Nutshell: Structure and Assembly of the Vaccinia Virion 39
I. Preface 40
II. Introduction 41
III. Vaccinia Virion Structure 50
IV. Vaccinia Virus Morphogenesis: An Overview 62
V. Formation of Factories 70
VI. Crescent Formation 70
VII. Immature Virion Formation: A Complex Process 90
VIII. IVrarrIVN Transition: Genome Encapsidation 95
IX. MV Formation 98
X. Transport, Occlusion, and Secondary Wrapping of MV 116
XI. Virion Proteins of Unknown Function 117
XII. Summary and Perspectives 118
Acknowledgments 119
References 119
Chapter 3: Human Papillomaviruses and Cervical Cancer 133
I. Introduction 133
II. Life Cycle of the Papillomaviruses 134
III. Evidence for an Essential Role of HPV in Cervical Carcinoma 137
IV. Pathogenesis of Cervical Carcinoma 139
V. Prophylactic Vaccination Against High-Risk HPV Infection 143
VI. Therapeutic Vaccination Against Cervical Carcinoma 144
VII. Prospects for Antiviral Treatments of Cervical Carcinoma 146
VIII. Conclusions and Prospects 147
Acknowledgments 148
References 148
Chapter 4: Plant Signal Transduction and Defense Against Viral Pathogens 169
I. Introduction 170
II. R Gene-Mediated Resistance to Viral Pathogens 172
III. Other Signaling Mechanisms Contributing to Viral Resistance 185
IV. Conclusions 188
Acknowledgments 188
References 189
Chapter 5: The Molecular Biology of Coronaviruses 201
I. Introduction 202
II. Taxonomy 203
III. Virion Morphology, Structural Proteins, and Accessory Proteins 206
IV. Viral Replication Cycle and Virion Assembly 224
V. RNA Synthesis 245
VI. Genetics and Reverse Genetics 264
Acknowledgments 268
References 268
Chapter 6: Chlorella Viruses 301
I. Introduction 302
II. Research History, Classification, and Specific Features 304
III. Virion Structure 306
IV. Virus Life Cycle 309
V. Virus Gene Expression: Immediate Early and Late Gene Expression 311
VI. Virus Protein Synthesis, Modification, and Degradation 314
VII. Diversity of Chlorella Virus Genomes 315
VIII. Cell Wall Digestion: Chitinase, Chitosanase, Polysaccharide Lyase, and beta-1, 3-Glucanase 325
IX. Glycosyltransferases and Synthesis of Polysaccharides and Fucose 328
X. Relationship of Chloroviruses to Other Viruses 332
XI. Perspectives 335
Acknowledgments 336
References 336
Chapter 7: Messenger RNA Turnover and its Regulation in Herpesviral Infection 345
I. Introduction 346
II. Regulation of Cytoplasmic mRNA Turnover in Mammalian Cells 346
III. Introduction to Herpesvirus-Induced Host Shutoff 365
IV. alpha-Herpesvirus-Induced mRNA Decay 365
V. gamma-Herpesvirus-Induced mRNA Decay 377
VI. Future Directions and Concluding Remarks 384
Acknowledgments 385
References 385
Index 403