Molecular Biology of Mitochondrial Transport Systems

Mitochondrial transport systems are essential to mitochondrial function and therefore to energy homeostasis within the cell. The book contains studies utilizing the techniques of biochemistry, physiology, molecular biology and genetics to reveal the structure and function of mitochondrial transport systems. It is divided into the following six sections: proton translocation - the uncoupling protein and the ATPase; carriers and transporters; mitochondrial ion channel; structure of the outer mitochondrial membrane channel, VDAC; VDAC, peripheral kinases and energy utilization; mitochondrial channels in humans and relationship to disease.