Molecular Biology of Mitochondrial Transport Systems

Proton Translocation: The Uncoupling Protein and the Atpase.- Molecular Studies of the Mitochondrial Uncoupling Protein.- Structure-Function Relationship in the Uncoupling Protein of Brown Adipose Tissue.- The Gating and Coupling Function of Mitochondrial H+ ATP Synthase. Role of Fo and F1 Subunits.- Carriers and Transporters.- Extension of the Mitochondrial Transporter Family.- The Tricarboxylate Carrier.- The Mitochondrial Pyruvate Carrier: The Mechanism of Substrate Binding.- Membrane Topology of the ADP/ATP Carrier from Mitochondria.- The Use of Ligand Binding Techniques to Identify Transport Proteins: The Characterization of the [125I]-Iodophenylarsine Oxide Receptor in Rat Mitochondrial Membranes.- Channel Properties of Mitochondrial Carriers.- Mitochondrial ion Channels.- A Minimal Kinetic Model of the Activity of the 107 pS Channel of the Inner Membrane of Mitochondria.- A Channel Model to Explain Regulation of the Mitochondrial Inner Membrane Anion Channel (IMAC).- The Mitochondrial Permeabilization Pore.- Mitochondrial Channels: An Integrated View.- Purification and Patch Clamp Analysis of Two Mitochondrial Channels.- The Mitochondrial Outer Membrane Contains at Least Two Distinct Channels.- ATP-Sensitive K+ Channel in Rat Liver Mitochondria: Functional Characteristics.- Structure of the Outer Mitochondrial Membrane Channel, VDAC.- Probing for the Voltage Sensor in a Mitochondrial Channel, VDAC, Using Site-Directed Mutagenesis.- Insights into the Structure of the Mitochondrial Channel, VDAC, Provided by Electron Microscopy.- Experimental Supports to a Sixteen-Strands Model of Transmembrane Arrangement of Mitochondrial Porin and Preliminary Results Concerning a Multigene Family in Drosophila melanogaster Related to Human Mitochondrial Porin.- VDAC, Peripheral K1Nases and Energy Utilization.- Structure and Function of the VDAC Ion Channel.- The Function of the Mitochondrial Outer Membrane Pore in the Regulation of Peripheral Kinases and Energy Metabolism.- Coordinated Regulation of Cerebral Glycolytic and Oxidative Metabolism Mediated by Mitochondrially Bound Hexokinase.- Influence of Macromolecules on the Permeability of Porin Pores and Dynamic Compartmentation of Adenine Nucleotides in the Mitochondrial Intermembrane Space.- Restrictions of Metabolite Permeation through the Outer Mitochondrial Membrane of Porin-Deficient Yeast Mutant.- Mitochondrial Channels in Humans and Relationship to Disease.- Role of Porin-Kinase Interactions in Disease.- Genes Encoding Human VDAC Proteins: Identification of Multiple Isoforms, Expression in Yeast and Chromosomal Localization.- "Porin 31HL" in the Plasmalemma of Human Cells: A VDAC Discussed as Part of a Chloride Channel Complex in Normal and Cystic Fibrosis B-Lymphocyte Cell Lines.