The Golgi Apparatus

State of the art 110 years after Camillo Golgi's discovery
Buch | Hardcover
VIII, 716 Seiten
2008 | 2008
Springer Wien (Verlag)
978-3-211-76309-4 (ISBN)

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This book summarizes all new data obtained after development of methods of Golgi complex sub fractionation, molecular biology and microscopy. It collects the full range of expertise, different points of view and different approaches. The book is devoted to molecular modes of the function of the Golgi apparatus as a whole, taking into account all experimental data. The book aims to make the functional organization of the Golgi apparatus more understandable.

General considerationsThe Golgi apparatus and main discoveries in the field of intracellular transportThe Golgi apparatus as a crossroads in intracellular trafficMain machineries operating at the Golgi apparatusSNAREsRabsCOPIICOPI: mechanisms and transport rolesArfs and Arls: models for Arf family members in membrane traffic at the GolgiCOG complexThe TRAPP complexThe role of Ca2+ in the regulation of intracellular transportGolgi glycosylation enzymesNucleotide sugar transporters of the Golgi apparatusLuminal lectinsThe Golgi ribbon and the function of the golginsFunctional cross talk between membrane trafficking and cell signallingThe role of the cytoskeleton in the structure and function of the Golgi apparatusThe dynamin-cortactin complex as a mediator of vesicle formation at the trans-Golgi networkThe geometry of organelles of the secretory pathwayMain transport stepsER-to-Golgi transportIntra-Golgi transportStructure and domain organization of the trans-Golgi networkGolgi-to-PM transportProtein transport from the trans-Golgi network to endosomesThe transport of soluble lysosomal hydrolases from the Golgi complex to lysosomesTransport of lysosomal membrane proteins from the Golgi complex to lysosomesRetrograde endosome-to-TGN transportRetrograde plasma membrane-to-Golgi apparatus transportInteractions between endocytosis and secretory transportOrigins of the regulated secretory pathwaySecretion and endocytosis in endothelial cellsFormation of mucin granulesGolgi apparatus and epithelial cell polarityGolgi apparatus inheritancePeculiarities of intracellular transport in different organismsFeatures of the plant Golgi apparatusYeast Golgi apparatusMorphodynamics of the yeast Golgi apparatusStructure and function of the Golgi organelle in parasitic protistsEvolution of the Golgi complexGeneral conclusions

Erscheint lt. Verlag 4.9.2008
Zusatzinfo VIII, 716 p.
Verlagsort Vienna
Sprache englisch
Maße 155 x 235 mm
Gewicht 1885 g
Themenwelt Naturwissenschaften Biologie Mikrobiologie / Immunologie
Naturwissenschaften Biologie Zellbiologie
Schlagworte Biology • Cell • Cytoskeleton • Development • Endoplasmatisches Reticulum • Enzym • Enzyme • enzymes • ER-to-Golgi Transport • Evolution • Golgi Complex • Golgi Enzymes • Intercellular Transport • Membrane • Microscopy • mitosis • Molecular Biology • Organelle • plants • Protein • proteins • Protists • Regulation • Sugar Transporters • yeast
ISBN-10 3-211-76309-0 / 3211763090
ISBN-13 978-3-211-76309-4 / 9783211763094
Zustand Neuware
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