Advances in Antiviral Drug Design

Buch | Hardcover

264 Seiten

2007
Elsevier Science Ltd (Verlag)
978-0-444-52173-6 (ISBN)

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Reviews the conceptual design and chemical synthesis of new antiviral compounds. This volume discusses their structure-activity relationship, mechanism and targets of action, pharmacological behavior, antiviral activity spectrum, and therapeutic potential for clinical use.

Regularly reviewing the "state-of-the-art" developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds. It discusses their structure-activity relationship, mechanism and targets of action, pharmacological behavior, antiviral activity spectrum, and therapeutic potential for clinical use.

Status presens of antiviral drugs and strategies, Part I: DNA viruses and retroviruses
Status presens of antiviral drugs and strategies, Part II: RNA viruses (except retroviruses)
Methylenecyclopropane analogues of nucleosides as anti-herpes agents
Synthesis and antiviral evaluation of broad spectrum orally active analogs of cidofovir and other acyclic nucleoside phosphonates
CCR5 antagonists for the treatment of HIV infection and AIDS
The medicinal chemistry of the DATA and DAPY series of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs)

Reihe/Serie	Advances in Antiviral Drug Design
Verlagsort	Oxford
Sprache	englisch
Maße	152 x 229 mm
Gewicht	550 g
Themenwelt	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
ISBN-10	0-444-52173-9 / 0444521739
ISBN-13	978-0-444-52173-6 / 9780444521736
Zustand	Neuware