Chromosomal Mutagenesis
Humana Press Inc. (Verlag)
978-1-58829-899-7 (ISBN)
Comprehensive and cutting-edge, Chromosomal Mutagenesis covers state-of-the-art techniques that are staged to expand, if not revolutionize, genetic analysis in the long neglected and relevant cell types.
Biallelic Gene Knockouts in Chinese Hamster Ovary Cells.- Highly Proficient Gene Targeting by Homologous Recombination in the Human Pre-B Cell Line Nalm-6.- Robust Cell Line Development Using Meganucleases.- Design and Testing of Zinc Finger Nucleases for Use in Mammalian Cells.- Gene Targeting in Drosophila and Caenorhabditis elegans With Zinc-Finger Nucleases.- Orpheus Recombination.- Transposon-Mediated Mutagenesis in Somatic Cells.- Insertional Mutagenesis of the Mouse Germline With Sleeping Beauty Transposition.- Conditional Gene Trapping Using the FLEx System.- Steps Toward Targeted Insertional Mutagenesis With Class II Transposable Elements.- Targeting Integration of the Saccharomyces Ty5 Retrotransposon.- Site-Specific Chromosomal Integration Mediated by ?C31 Integrase.- Triplex-Mediated Gene Modification.- Allelic Exchange of Unmarked Mutations in Mycobacterium Tuberculosis.- Mycobacterial Recombineering.- Chromosomal Engineering of Clostridium Perfringens Using Group II Introns.
| Reihe/Serie | Methods in Molecular Biology ; 435 |
|---|---|
| Zusatzinfo | 3 Illustrations, color; 36 Illustrations, black and white; XVI, 236 p. 39 illus., 3 illus. in color. |
| Verlagsort | Totowa, NJ |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete |
| Medizin / Pharmazie ► Studium | |
| Naturwissenschaften ► Biologie ► Biochemie | |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| ISBN-10 | 1-58829-899-X / 158829899X |
| ISBN-13 | 978-1-58829-899-7 / 9781588298997 |
| Zustand | Neuware |
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