The Leydig Cell in Health and Disease

Historical.- A History of Leydig Cell Research.- Cell Biology.- Structural and Histological Analysis of Leydig Cell Steroidogenic Function.- Fetal Leydig Cells.- Regulation of Leydig Cells During Pubertal Development.- The Human Leydig Cell.- Dynamics of Leydig Cell Regeneration After EDS.- Aging and the Decline of Androgen Production.- Steroidogenesis.- Regulation of Leydig Cell Cholesterol Metabolism.- The Role of StAR in Leydig Cell Steroidogenesis.- Steroidogenic Enzymes in Leydig Cells.- Development of Leydig Cell Steroidogenesis.- Peripheral Testosterone Metabolism.- Leydig Cell Aromatase.- The Role of Estrogen Sulfotransferase in Leydig Cells.- Endocrinology of Leydig Cells in Nonmammalian Vertebrates.- Regulation.- The Luteinizing Hormone Receptor.- Insights Into Leydig Cell Function From Mice With Genetically Modified Gonadotropin Action.- Growth Factors in Leydig Cell Function.- Insulin-Like Peptide 3 in Leydig Cells.- Neuronal Signaling Molecules and Leydig Cells.- Regulation of Leydig Cell Function as it Pertains to the Inflammatory Response.- Activins and Leydig Cell Development Differentiation, and Disease.- Transcription Factors as Regulators of Gene Expression During Leydig Cell Differentiation and Function.- Androgen Receptor in Leydig Cell Function and Development.- Physiology and Applied Aspects.- Fluid Exchange and Transport of Hydrophilic Factors in the Testis.- Immortalized Leydig Cell Lines as Models for Studying Leydig Cell Physiology.- Induction of Leydig Cell Tumors by Xenobiotics.- Environmental Factors That Disrupt Leydig Cell Steroidogenesis.- The Leydig Cell as a Target for Male Contraception.- Clinical Evaluation of Leydig Cell Function.