Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases

Apoptotic Pathways and Their Regulation.- Mechanisms of Anticancer Drug Action.- Death Receptor Pathways As Targets for Anticancer Therapy.- Caspases; Modulators of Apoptosis and Cytokine Maturation — Targets for Novel Therapies.- The Intrinsic (Mitochondrial) Death Pathway and New Cancer Therapeutics: Bcl-2 Family in Focus.- Survivin, other IAPs, Smac/Diablo, and Omi/Htra2 — Modulation of the Advancing Apoptotic Process.- The Life Cycle of P53: A Key Target in Drug Development.- Growth Factors, Receptors, and Kinases: Their Exploration to Target Cancer.- Targets for Apoptotic Intervention in Rheumatoid Arthritis.- Therapeutic Inhibition of Apoptosis Caused by Stroke.- Monoclonal and Bispecific Antibodies as Novel Therapeutics.- Targeting the Proteasome in Cancer Therapy.- D-RNAi-Based Therapeutics.- Nuclear Transcription Factor-?B: A Drug Target for all Seasons.- Monitoring of Programmed cell Death in Vivo and in Vitro,—New and Old Methods of Cancer Therapy Assessment.- Current Strategies in Tumor-Targeting.- Strategies of Protection of Normal Cells During Chemo- and Radio-Therapy Based on Modulation of Cell Cycle and Apoptotic Pathways.