Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases

Chapter I: Apoptotic Pathways and Their Regulation Chapter II: Mechanisms of Anticancer Drug Action Chapter III: Death Receptor Pathways as Targets For Anticancer Therapy Chapter IV: Caspases; Modulators of Apoptosis and Cytokine Maturation – Targets For Novel Therapies Chapter V: The Intrinsic (Mitochondrial) Death Pathway and New Cancer Therapeutics: BCL-2 Family In Focus Chapter VI: Survivin, Other OAPS, SMAC/DIABLE, and OMI/HTRA2 – Modulation of the Advancing Apoptotic Process Chapter VII: The Life Cycle of p52: A Key Target in Drug Development Chapter VIII: Growth Factors, Receptors, and Kinases: Their Exploration To Target Cancer Chapter IX: Targets For Apoptotic Intervention in Rheumatoid Arthritis Chapter X: Therapeutic Inhibition of Apoptotis Caused By Stroke Chapter XI: Monoclonal and Bispecific Antibodies as Novel Therapeutics Chapter XII: Targeting the Proteasome in Cancer Therapy Chapter XIII: D-RNA i-Based Therapeutics Chapter XIV: Nuclear Transcription Factor – kB: A Drug Target For All Seasons Chapter XV: Monitoring of Programmed Cell Death In Vivo and In Vitro, - New and Old Methods of Cancer Therapy Assessment Chapter XVI: Current Strategies In Tumor-Targeting Chapter XVII: Strategies of Protection of Normal Cells During Chemo- and Radio- Therapy Based On Modulation of Cell Cycle and Apoptotic Pathways Summary Table: New Therapeutic Agents Designed By Exploring the Recent Progress On Our Understanding of Cell Death Pathways