Dissecting the Molecular Anatomy of Tissue

Buch | Hardcover
XVIII, 230 Seiten
2004 | 2005
Springer Berlin (Verlag)
978-3-540-22006-0 (ISBN)

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Dissecting the Molecular Anatomy of Tissue -
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The book provides an updated overview of molecular analysis of human tissues, and the impact this analysis has on diagnosis and prognosis of human diseases. Special emphasis is placed on human cancer and the future directions of the field. Methods of handling clinical tissue samples, including the impact of handling on subsequent molecular analysis, are also discussed. In addition, detailed protocols for molecular analysis of DNA, RNA and protein, with special emphasis on molecular analysis of highly complex human tissue samples containing mixtures of cell populations, are provided.

Michael Emmert-Buck, MD, PhD is Chief of the Pathogenetics Unit, Laboratory of Pathology, NCI. He received his MD and PhD degrees from Wayne State University and completed his training in anatomic pathology at the NCI. Dr. Emmert-Buck became Chief of the Pathogenetics Unit in 1996.

Clinkal Issues and Tissue Processing.- Molecular Pathology Laboratory of the Future.- Clinical Utilities of Microdissected Samples.- Tissue Processing.- Sample Management and Tracking.- Methods of Tissue Microanalysis.- Tissue Microarrays.- Molecular Analysis of Microdissected Samples.- Methods of Microdissection and New Technologies.- Standard Diagnostic Techniques.- DNA Applications.- mRNA Applications.- Proteomic Applications.- Protocols for Tissue Handling and Molecular Analysis.

From the reviews:

"This book, divided into four sections, provides an updated overview of the molecular analysis of human tissues ... . Special emphasis is placed on human cancer and the future directions of the field. ... The detailed protocols make this book particularly useful for scientists and clinicians interested in the analysis of tissue samples." (CLI - Clinical Laboratory International, Vol. 29 (5), 2005)

Erscheint lt. Verlag 26.11.2004
Reihe/Serie Principles and Practice
Zusatzinfo XVIII, 230 p.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 480 g
Themenwelt Naturwissenschaften Biologie Mikrobiologie / Immunologie
Naturwissenschaften Biologie Zellbiologie
Schlagworte Analyse, molekulare • analysis, molecular • DNA • Gewebe (Biologie) • Gewebe, Präparierung, Sektion • microdissection • Molekularbiologie • nucleid acids • Nukleinsäuren • Proteine • proteins • RNA • tissue
ISBN-10 3-540-22006-2 / 3540220062
ISBN-13 978-3-540-22006-0 / 9783540220060
Zustand Neuware
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