Glycobiology of Innate Immunology -  Cheorl-Ho Kim

Glycobiology of Innate Immunology (eBook)

eBook Download: PDF
2022 | 1st ed. 2022
XIX, 656 Seiten
Springer Singapore (Verlag)
978-981-16-9081-5 (ISBN)
Systemvoraussetzungen
149,79 inkl. MwSt
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This book presents the latest knowledge and the most recent research results on glycobiology of innate immunology. Innate immunity is the crucial part of the immunological defense system that exerts their distinct functions through binding to certain functional glycoproteins. They play a role in various human diseases and also function against microbial invaders and self-associated molecular patterns. Co-regulated expression of glycan-binding is associated with many biological components such as cellular oncotransformation, phenotype change, neuronal or embryonic development, regulation of cell division, cell-cell interaction, cell attachment, adhesion, and motility, and intracellular signaling via protein-carbohydrate or carbohydrate-carbohydrate interactions.

This book opens by providing the key background on glycans in innate immunity and its mechanisms behind the Dendritic cell interactions during infection and inflammation are examined in depth, and the concluding chapter is devoted to signaling tumor immunotherapy. Up-to-date information is then presented on all aspects of glycan structure-recognizing signaling. The book should assist in the further development of new strategies against emerging infectious agents and intractable diseases.




Prof. Cheorl-Ho Kim

Molecular and Cellular Glycobiology Unit, Department of Biological Sciences, Sungkyunkwan University


This book presents the latest knowledge and the most recent research results on glycobiology of innate immunology. Innate immunity is the crucial part of the immunological defense system that exerts their distinct functions through binding to certain functional glycoproteins. They play a role in various human diseases and also function against microbial invaders and self-associated molecular patterns. Co-regulated expression of glycan-binding is associated with many biological components such as cellular oncotransformation, phenotype change, neuronal or embryonic development, regulation of cell division, cell-cell interaction, cell attachment, adhesion, and motility, and intracellular signaling via protein-carbohydrate or carbohydrate-carbohydrate interactions.This book opens by providing the key background on glycans in innate immunity and its mechanisms behind the Dendritic cell interactions during infection and inflammation are examined in depth, and the concluding chapter is devoted to signaling tumor immunotherapy. Up-to-date information is then presented on all aspects of glycan structure-recognizing signaling. The book should assist in the further development of new strategies against emerging infectious agents and intractable diseases.
Erscheint lt. Verlag 31.3.2022
Zusatzinfo XIX, 656 p. 1 illus.
Sprache englisch
Themenwelt Studium 2. Studienabschnitt (Klinik) Humangenetik
Naturwissenschaften Biologie Genetik / Molekularbiologie
Naturwissenschaften Biologie Zellbiologie
Schlagworte CD22 • dendritic cell • galectins • Glycan regulation • Glycans • Glycan structure-recognizing • glycobiology • Innate immunology • Lectins • Trafficking • Tumor immunotherapy
ISBN-10 981-16-9081-2 / 9811690812
ISBN-13 978-981-16-9081-5 / 9789811690815
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