Molecular Diagnostics of Cancer

The Polymerase Chain Reaction: Methodology and Diagnostic Potential.- Gene Loss as Marker in Tumor Development: Considerations on the Origin of Specific Brain Tumors Due to Combinant Loss of Function Mutations of Tumor Suppressor Genes.- p53: Oncogene, Tumor Suppressor, or Both?.- Tumor Genome Screening by Multilocus DNA Fingerprints as Obtained by Simple Repetitive Oligonucleotide Probes.- Activation of ras Oncogenes in Human Tumours.- Laboratory Techniques in the Investigation of Human Papillomavirus Infection.- Detection of Minimal Residual Leukemia by Polymerase Chain Reactions.- A Dominant Metastogene Confers Metastatic Potential to Tumor Cells.- Progression in Human Melanoma Is Accompanied by the Altered Expression of Cell Adhesion Molecules.- Structure, Function and Expression of the CEA Gene Family: Diagnostic and Therapeutic Implications.- Membrane Proteins as Markers for Normal and Neoplastic Endocrine Cells.- Biological and Clinical Relevance of the Tumor-Associated Serine Protease uPA.- Analysis of Growth Regulatory Pathways in Human Neuro-Oncology.- HER-2/Neu/c-ERB-B2 Amplification: Clinical Relevance in Mammary Carcinoma.- Cytokine-Mediated Regulation of Growth Factor Receptors (EGF-R and erb-B2) in Pancreatic Tumors.- Chimeric CEA-Specific Antibody Fragments and Anti-idiotypic Antibodies for Immunoscintigraphy and New Therapeutic Approaches to Colorectal Carcinomas.- Tumor Localization by Immunoscintigraphy: Potential and Limitations.