Lipid Transfer in Lipoprotein Metabolism and Cardiovascular Disease -

Lipid Transfer in Lipoprotein Metabolism and Cardiovascular Disease

Xian-Cheng Jiang (Herausgeber)

Buch | Softcover
234 Seiten
2021 | 1st ed. 2020
Springer Verlag, Singapore
978-981-15-6084-2 (ISBN)
192,59 inkl. MwSt
This book provides an up-to-date review of the fundamentals of lipid metabolism and its role in cardiovascular diseases. Focusing on lipid transfer proteins in the circulation and cells, the role of important lipid transporters, the effect of recently discovered lipid binding proteins, and the link between lipid metabolism disorders and cardiovascular diseases, it covers phospholipid transfer protein, cholesteryl ester transfer protein, lipopolysaccharide binding protein, microsomal triglyceride transfer protein, ABC binding cassette members, and more. The book offers graduate students and researchers a coherent overview of lipid transfer and transport, as well as the limitations of current research in the field, and promotes further studies on cardiovascular diseases, as well as pharmaceutical research on drug discovery based on lipid transfer, transport, and binding.

Dr. Xian-Cheng Jiang (PhD) is a Distinguished Professor of State University of New York (SUNY). He is working at the Department of Cell Biology, SUNY Downstate Health Sciences University. His research focuses on lipid metabolism and  metabolic diseases, such as atherosclerosis, metabolic syndrome, obesity and liver steatosis, particularly how phospholipid metabolism influences plasma lipoprotein metabolism, cell membrane lipid composition and function, and the development of metabolic diseases.

Chapter 1: Impact of Phospholipid Transfer Protein in Lipid Metabolism and Cardiovascular Diseases.- Chapter 2: Cholesteryl Ester Transfer Protein and Lipid Metabolism and Cardiovascular Diseases.- Chapter 3: Lipopolysaccharide Binding Protein and Bactericidal/Permeability-increasing Protein in Lipid Metabolism and Cardiovascular Diseases.- Chapter 4: Microsomal Triglyceride Transfer Protein: From Lipid Metabolism to Metabolic Diseases.- Chapter 5: Circadian-Clock Regulation on Lipid Metabolism and Metabolic Diseases.- Chapter 6: ABC Transporters, Cholesterol Efflux and Implications for Cardiovascular Diseases.- Chapter 7: Apolipoprotein M: research progress and clinical perspective.- Chapter 8: Recent Advances in the Critical Role of the Sterol Efflux Transporters ABCG5/G8 in Health and Disease.- Chapter 9: Proprotein Convertase Subtilisin/Kexin-type 9 and Lipid Metabolism.- Chapter 10: LDL and HDL Oxidative Modification and Atherosclerosis.- Chapter 11: Rare Diseases Related with Lipoprotein Metabolism.- Chapter 12: Preβ1 High Density Lipoprotein in Cardiovascular Diseases.- Chapter 13: CGI-58: Versatile Regulator of Intracellular Lipid Droplet Homeostasis.- Chapter 14: Mfsd2a, a physiologically important lysolipid transporter in brain and eye.

Erscheinungsdatum
Reihe/Serie Advances in Experimental Medicine and Biology ; 1276
Zusatzinfo 27 Illustrations, color; 11 Illustrations, black and white; VIII, 234 p. 38 illus., 27 illus. in color.
Verlagsort Singapore
Sprache englisch
Maße 178 x 254 mm
Themenwelt Studium 1. Studienabschnitt (Vorklinik) Physiologie
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Zellbiologie
Schlagworte High density lipoprotein revaluation • Lipid binding proteins • Lipid transfer proteins • Lipid transporters • Lipoprotein modification and its consequence • Rare diseases in lipoprotein metabolism
ISBN-10 981-15-6084-6 / 9811560846
ISBN-13 978-981-15-6084-2 / 9789811560842
Zustand Neuware
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