Spin-Label Electron Paramagnetic Resonance Spectroscopy

Derek Marsh has published hundreds of original papers in this area, over its 40-year period of development, and has also contributed several reviews and book chapters in this area. He is coauthor of the (now out-of-print) student-level textbook Magnetic Resonance of Biomolecules (1976) and author of the reference work Handbook of Lipid Bilayers (Second Edition to be published in spring 2012). His studies were performed at the University of Oxford, and he earned a B.A. and M.A. in Physics, and a D.Phil. in Magnetic Resonance (1971). His graduate research focused on magnetic resonance (ESR) spectroscopy applied to magnetic investigations of transition metals in solids. He was a postdoctoral researcher in the Astbury Department of Biophysics at the University of Leeds, using magnetic resonance to study the structure and function of phospholipid bilayers and biological membranes. He also had appointments at the National Research Council of Canada, Max-Planck Institute for Biophysical Chemistry, and the Department of Biochemistry at the University of Oxford. He has been on the permanent research staff of the Max-Planck Institute for Biophysical Chemistry since 1975, and was Visiting Professor at the University of Leeds from 1997 to 2010. Dr. Marsh has been on the editorial board of numerous journals, including Chemistry and Physics of Lipids, Biochimica et Biophysica Acta, Biochemical Journal, and Biophysical Journal. He has authored or co-authored over 425 scientific papers to date.

1. Introduction. 2. The Nitroxide EPR Spectrum. 3. Hyperfine Interactions and g-Vaules. 4. Polarity Dependance. 5. Spin Relaxation Theory. 6. EPR Lineshape Theory. 7. Dynamics and Rotational Diffusion. 8. Dynamics and Orientational Ordering (Liquid Crystals and Membranes). 9. Spin-Spin Interactions. 10. Spin-Latice Relaxation. 11. Nonlinear and Saturation-Transfer EPR. 12. Saturation-Recovery EPR and ELDOR. 13 Spin-Echo EPR. 14. ESEEM and ENDOR: Hyperfine Spectroscopy. 15. Distance Measurements. 16. Site-Directed Spin Labelling (SDSL)