Integrated Drug Discovery Technologies - Houng-Yau Mei, Anthony W. Czarnik

Integrated Drug Discovery Technologies

Buch | Hardcover
596 Seiten
2002
Crc Press Inc (Verlag)
978-0-8247-0649-4 (ISBN)
309,95 inkl. MwSt
Presents a global overview of various drug development technologies. This book combines integration of contemporary mechanization with strategies in drug delivery. It includes topics such as target identification and validation, functional genomics, microfabrication techniques, integrated proteomics technologies, and high throughput screening.
Integrated Drug Discovery Technologies provides a global overview of emerging drug development technologies by presenting and integrating new techniques from the disciplines of chemistry, biology, and computational sciences. It combines integration of contemporary mechanization with strategies in drug delivery. Topics include: functional genomics, microfabrication techniqes, integrated proteomics technologies, high throughput screening, and fluorescence correlation spectroscopy methods.

Mei, Houng-Yau; Czarnik, Anthony W.

From gene to screen: target identification and validation Coupling Genotype to Phenotype; functional genomics; integrated proteomics technologies; where science meets silicone - microfabrication techniques and their scientific applications; SNP scoring for drug discovery applications; protein display chips; integrated proteomics technologies and in vitro validation of molecular tests. High throughput screening: high throughput screening as a discovery resource; fluorescence correlation spectroscopy (FCS) and FCS-related confocal fluorimetric methods (FCS + plus) multiple read-out options or miniaturized screening; homogeneous time-resolved fluorescence (HTRF); ADME-tox screening in drug discovery; screening lead compounds in the post-genomic era - an integrated approach to knowledge building from living cells.

Erscheint lt. Verlag 19.3.2002
Verlagsort Bosa Roca
Sprache englisch
Maße 152 x 229 mm
Gewicht 907 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Naturwissenschaften Biologie
Technik
ISBN-10 0-8247-0649-8 / 0824706498
ISBN-13 978-0-8247-0649-4 / 9780824706494
Zustand Neuware
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