Peptide Self-Assembly
Humana Press Inc. (Verlag)
978-1-4939-7809-0 (ISBN)
Authoritative and cutting-edge, Peptide Self-Assembly: Methods and Protocols aims to capture modern methods that span the breadth of the exciting and expanding field of peptide self-assembly.
Methods for Structural Analysis of Aggregates Formed by Self-Assembling Peptides.- Solid state NMR Structura.- Characterization of Self-assembled Peptides With Selective 13C and 15N Isotopic LabelsATR-FTIR Analysis of Amyloid Proteins.- Imaging Protein Fibers at the Nanoscale and In Situ.- Replica Exchange Molecular Dynamics: A Practical Application Protocol with Solutions to Common Problems and a Peptide Aggregation and Self-Assembly Example.- An Aggregate Weight-normalized thioflavin-T Measurement Scale For Characterizing Polymorphic Amyloids And Assembly Intermediates.- Nanoparticle Tracking for Protein Aggregation Research.- Peptide Self-assembly Measured using Fluorescence Correlation Spectroscopy.- A General Method to Prepare Peptide-based Supramolecular Hydrogels.- Recursive Directional Ligation Approach for Cloning Recombinant Spider Silks.- Synthesis of Mikto-Arm Star Peptide Conjugates.- Synthesis and Evaluation of Self—Assembled Nanostructures of Peptide—π chromophore conjugates.- Programmable Fabrication of Multi-layer Collagen Nanosheets of Defined Composition.- Practical Considerations in the Design and use of Immunologically Active Fibrillar Peptide Assemblies.- Microwave-assisted Synthesis and Immunological Evaluation of Self-Assembling Peptide Vaccines.- Preparation and Screening of Catalytic Amyloid Assemblies.-Self-assembly of Filamentous Cell Penetrating Peptides for Gene Delivery.- Biogelx: Cell Culture on Gels based on Aromatic Peptide Amphiphiles.- Production and use of Recombinant Aβ for Aggregation Studies.- Disaggregation of Ab42 for Structural and Biochemical Studies.- Preparation of Stable Amyloid-β Oligomers Without Perturbative Methods.- Discriminating Strains of Self-Propagating Protein Aggregates Using a Conformational Stability Assay.- Model Phospholipid Liposomes to Study the b-Amyloid-Peptide-Induced Membrane Disruption.- Using Molecular Tweezers to Remodel Abnormal Protein Self-assembly and Inhibit the Toxicity of Amyloidogenic Proteins.- Incorporation of an azobenzene b-turn Peptidomimetic into Amyloid-b to Probe Potential Structural Motifs Leading to b-sheet self-assembly.- Solid State NMR Studies of Amyloid Materials: A Protocol to Define an Atomic Model of Aβ(1–42) in Amyloid Fibrils.- Experimental and Computational Protocols for Studies of Cross-seeding Amyloid Assemblies.
Erscheinungsdatum | 16.05.2018 |
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Reihe/Serie | Methods in Molecular Biology ; 1777 |
Zusatzinfo | 53 Illustrations, color; 77 Illustrations, black and white; XV, 452 p. 130 illus., 53 illus. in color. |
Verlagsort | Totowa, NJ |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
Schlagworte | amyloid pathologies • extracellular matrix proteins • protein self-assembly phenomena • Solid-State NMR • Spectroscopic |
ISBN-10 | 1-4939-7809-8 / 1493978098 |
ISBN-13 | 978-1-4939-7809-0 / 9781493978090 |
Zustand | Neuware |
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