2-Oxoglutarate-Dependent Oxygenases (eBook)

Biochemical Diversity of 2-Oxoglutarate Dependent Oxygenases; Introduction to Structural Studies on 2-Oxoglutarate Dependent Oxygenases and Related Enzymes; Mechanisms of 2-Oxoglutarate-Dependent Oxygenases; Synthetic Models of 2-Oxoglutarate-Dependent Oxygenases; Collagen Hydroxylases; The Role of 2-Oxoglutarate-Dependent Oxygenases in Hypoxia Sensing; JmjC Lysine Demethylases; AlkB and its Homologues—DNA Repair and Beyond; RNA Demethylation by FTO and ALKBH5; Role of ALKBH8 in the Synthesis of Wobble Uridine Modifications in tRNA; The TET/JBP Family of Nucleic Acid Base-Modifying 2-Oxoglutarate and Iron-Dependent Dioxygenases; 2-Oxoglutarate-Dependent Hydroxylases Involved in DNA Base J (β-D-glucopyranosyloxymethyluracil) Synthesis; Dioxygenases of Carnitine Biosynthesis: 6-N-Trimethyllysine and γ-Butyrobetaine Hydroxylases; Phytanoyl-CoA Hydroxylase: a 2-Oxoglutarate Dependent Dioxygenase Crucial for Fatty Acid Alpha-Oxidation in Humans; Role of 2-Oxoglutarate Dependent Oxygenases in Flavonoid Metabolism; Gibberellin Metabolism; 2-Oxoglutarate Dependent Oxygenases of Cephalosporin Synthesis; Recent Advances in the Structural and Mechanistic Biology of Non-Heme Fe(II), 2-Oxoglutarate, and O2 Dependent Halogenases; Isopenicillin N Synthase; 1-Aminocyclopropane-1-Carboxylic Acid Oxidase; 4-Hydroxyphenylpyruvate Dioxygenase and Hydroxymandelate Synthase: 2-Oxo Acid-Dependent Oxygenases of Importance to Agriculture and Medicine