Metalloprotein Active Site Assembly (eBook)

Editors Michael K. Johnson, University of Georgia, Athens, GA, USA Robert A. Scott, University of Georgia, Athens, GA, USA

Contributors ix

Series Preface xiii

Volume Preface xv

Part 1: Assembly and Trafficking of Simple Fe-S Clusters 1

Nif System for Simple [Fe-S] Cluster Assembly in Nitrogen-Fixing Bacteria 3
Patricia C. Dos Santos and Dennis R. Dean

Iron-Sulfur Cluster Assembly in Bacteria and Eukarya using the ISC Biosynthesis Machinery 17
Sandrine Ollagnier de Choudens and Hélène Puccio

The Suf System in Archaea, Bacteria, and Eukaryotic Organelles 37
Guangchao Dong, Savannah Witcher, F. Wayne Outten and Marinus Pilon

Roles of Class II Glutaredoxins in the Maturation of Fe-S Proteins 53
Jonathan Przybyla-Toscano, Thomas Roret, Jérémy Couturier and Nicolas Rouhier

Part 2: Assembly of Complex and Heterometallic Fe-S Cluster Active Sites 73

Nitrogenase Metallocluster Assembly 75
Nathaniel S. Sickerman, Lee A. Rettberg, Yilin Hu and Markus W. Ribbe

Metallocluster Assembly: Maturation of [FeFe]-Hydrogenases 93
Giorgio Caserta, Ludovic Pecqueur, Cecilia Papini and Marc Fontecave

CO Dehydrogenase and Acetyl-CoA Synthase 111
Holger Dobbek

Part 3: Assembly of Homometallic and Heterometalic Cu Cluster Active Sites 123

Assembly of Dinuclear Copper Center in Tyrosinases and Hemocyanins 125
Nobutaka Fujieda and Shinobu Itoh

Multicopper Oxidases 139
Daniel J. Kosman

Assembly of the Redox-Active Metal Centers of Cytochrome c Oxidase 157
Eva Nyvltova, Antoni Barrientos and Jonathan Hosler

CuA and CuZ Center Assembly in Nitrous Oxide Reductase 185
Sofia R. Pauleta and Isabel Moura

MoCu CO Dehydrogenase and its Active-Site Assembly 197
Frank Mickoleit

Part 4: Assembly of Homometallic and Heterometallic Mn Clusters 213

Homo- and Heterometallic Dinuclear Manganese Proteins: Active Site Assembly 215
Gustav Berggren, Daniel Lundin and Britt-Marie Sjöberg

Biogenesis and Assembly of the CaMn4O5 Core of Photosynthetic Water Oxidases and Inorganic Mutants 233
Colin Gates, Gennady Ananyev and G. Charles Dismukes

Part 5: Assembly of Homometallic and Heterometallic Ni Clusters 249

Urease Activation 251
Robert P. Hausinger

Insights into [NiFe]-Hydrogenase Active Site Metallocluster Assembly 261
Robert Gary Sawers and Constanze Pinske

Part 6: Assembly of Cofactors for Binding Active-Site Metal Centers 273

Moco in Mo/W Enzymes 275
Silke Leimkühler

Heme Biosynthesis 299
Amy E. Medlock and Harry A. Dailey

Siroheme Assembly and Insertion to Nitrite and Sulfite Reductase 315
M. Elizabeth Stroupe and Martin J. Warren

Biosynthesis of Coenzyme F430 and the Posttranslational Modification of the Active Site Region of Methyl-Coenzyme M Reductase 323
Steven O. Mansoorabadi, Kaiyuan Zheng and Phong D. Ngo

Coenzyme B12 Biosynthesis in Bacteria and Archaea 335
Theodoric A. Mattes, Jorge C. Escalante-Semerena, Evelyne Deery and Martin J. Warren

Crosslinked Cys-Tyr Free Radical Redox Cofactor 361
James W. Whittaker

Topaquinone Biogenesis and Lysyl Tyrosine Quinone Biogenesis in Cu Amine Oxidases 375
David M. Dooley, Doreen E. Brown and Eric M. Shepard

Index 389