Symmetry, Spectroscopy, and Crystallography (eBook)

Robert Glaser is Emeritus Professor of Chemistry at Ben-Gurion University of the Negev, Beer-Sheva, Israel. He also holds an appointment as Visiting Professor in the Cross-Border Program in Biological Chemistry Budejoice (Budaweis), Czech Republic, administered by the University of South Bohemia/Universität Johannes Kepler in Linz, Austria. He also teaches at the Feinberg Graduate School of the Weizmann Institute of Science in Rehovot, Israel. Robert Glaser received his BA in chemistry at the University of Pennsylvania (USA) in 1963. Upon graduation he worked as a development chemist in the Structural Adhesives Division of the Pittsburg Plate Glass Company. Concurrently, he undertook part-time MSc studies in polymer chemistry at the Polytechnic Institute of Brooklyn, USA. After three years he began full-time studies, graduating Rutgers State University, USA, in 1969. From 1969 - 1971 he spent a two-year postdoctoral fellowship at Princeton University (USA) under guidance of Prof. P. von Rague Schleyer and Prof. R. Landgridge. After immigrating to Israel in 1971, he built up a new Department of Chemistry at the recently established University of the Negev in Beer-Sheva, where he became full professor in 1997. He has authored over 100 publications on the topic of organic and inorganic stereochemistry, molecular modeling, computer assisted drug design, and structure determination via NMR spectroscopic techniques.

Symmetry/Pseudosymmetry; Chirality in Molecules, Nature, and in the Cosmos
Enantiospecificity of Pheromones, Sweetners, Fragrances, and in Drug Discovery
Bonding Parameters and the Effect of Local Environment upon Molecular Structure
Historical Development of Structural Chemistry: From Alchemy to Modern Structural Theory
Chrioptical Properties
Symmetry Comparison of Molecular Subunits: Symmetry in Nuclear Magnetic Resonance Spectroscopy and in Dynamic NMR
Prochirality, Asymmetric Hydrogenation Reactions and the Curtin-Hammett Principle
Stereogenic Elements, Chirotopicity, Permutational Ismers, and Gear-Like Correlated Motion of Molecular Subunits
Symmetry in Extended Periodic Arrays of Molecular Crystals, and the Relevance of Pensrose Tiling Rules for Non-Periodic Quazicrystal Packing
Multiple Molecules in the Asymmetric Unit, 'Faking It'; Pseudosymmetry Emulation of Achiral Higher Order Space Filling in Kryptoracemate Chiral Crystals
Platonic-Solid Geometry Molecules and Crystallographic Constraints upon Molecular Geometry, Symmetry Distortions from Ideality
Solid-State NMR Spectroscopy/X-Ray Crystallographic Investigation of Conformational Polymorphism/Pseudopolymorphism in Crystalline Stable and Labile Hydrated Drugs
NMR Spectroscopic Differentiation of Diastereomeric Isomers Having Special Positions of Molecular Symmetry
Stereochemistry of Medium Ring Conformations
The Pharmacophore Method
The X-Ray Structure-Based Method of Rational Design
Helical Stereochemistry

Index