Genomics of Pattern Recognition Receptors - Anton G. Kutikhin, Arseniy E. Yuzhalin

Genomics of Pattern Recognition Receptors

Applications in Oncology and Cardiovascular Diseases
Buch | Softcover
XI, 185 Seiten
2015 | 1. Softcover reprint of the original 1st ed. 2013
Springer Basel (Verlag)
978-3-0348-0794-4 (ISBN)
149,98 inkl. MwSt
This book details the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, coverage examines the structure and function of Toll-like and NOD-like receptors.
This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.

The Biology of Toll-like Receptors and NOD-like Receptors: Toggles of Inflammation.- Pattern Recognition Receptors, Gene Polymorphisms, and Cancer: A Double-Edged Sword.- Structural Genomic Variation in Toll-Like Receptor 4 and Cancer.- Structural Genomic Variation in Other Toll-like Receptors and Cancer.- Structural Genomic Variation in Toll-Like Receptor Signaling Pathway and Cancer.- Structural Genomic Variation in Toll-like Receptor Pathway and Prostate Cancer.- Structural Genomic Variation in NOD-Like Receptors and Cancer.- Structural Genomic Variation in Pattern Recognition Receptors and Cardiovascular Diseases.- Hot Spots In the Field: Where Should We Go.

From the reviews:

"This book comprehensively covers the polymorphism of genes-encoding pattern recognition receptors (PRRs) ... . The book is intended for immunologists, cancer researchers, cardiologists, epidemiologists, microbiologists, and geneticists, as well as PhD, graduate, and undergraduate students of biomedical faculties and their lecturers. This is a unique book that analyzes the field of PRR genomics and its practical applications. ... This book will be quite useful for a very wide audience." (Omer Iqbal, Doody's Book Reviews, March, 2014)

Erscheinungsdatum
Zusatzinfo XI, 185 p.
Verlagsort Basel
Sprache englisch
Maße 155 x 235 mm
Gewicht 314 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Studium Querschnittsbereiche Infektiologie / Immunologie
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Schlagworte Biomedical and Life Sciences • Cancer • Cancer Research • Cardiology • Cardiovascular Diseases • Human genetics • immune response • immunology • NOD-like receptors • Oncology • Pathogen-associated patterns • receptors • Toll-like receptors
ISBN-10 3-0348-0794-5 / 3034807945
ISBN-13 978-3-0348-0794-4 / 9783034807944
Zustand Neuware
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