Genomics of Pattern Recognition Receptors

Applications in Oncology and Cardiovascular Diseases
Buch | Hardcover
XI, 185 Seiten
2013 | 2013
Springer Basel (Verlag)
978-3-0348-0687-9 (ISBN)

Lese- und Medienproben

Genomics of Pattern Recognition Receptors - Anton G. Kutikhin, Arseniy E. Yuzhalin
171,19 inkl. MwSt
This book details the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, coverage examines the structure and function of Toll-like and NOD-like receptors.
This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.

The Biology of Toll-like Receptors and NOD-like Receptors: Toggles of Inflammation.- Pattern Recognition Receptors, Gene Polymorphisms, and Cancer: A Double-Edged Sword.- Structural Genomic Variation in Toll-Like Receptor 4 and Cancer.- Structural Genomic Variation in Other Toll-like Receptors and Cancer.- Structural Genomic Variation in Toll-Like Receptor Signaling Pathway and Cancer.- Structural Genomic Variation in Toll-like Receptor Pathway and Prostate Cancer.- Structural Genomic Variation in NOD-Like Receptors and Cancer.- Structural Genomic Variation in Pattern Recognition Receptors and Cardiovascular Diseases.- Hot Spots In the Field: Where Should We Go.

From the reviews:

"This book comprehensively covers the polymorphism of genes-encoding pattern recognition receptors (PRRs) ... . The book is intended for immunologists, cancer researchers, cardiologists, epidemiologists, microbiologists, and geneticists, as well as PhD, graduate, and undergraduate students of biomedical faculties and their lecturers. This is a unique book that analyzes the field of PRR genomics and its practical applications. ... This book will be quite useful for a very wide audience." (Omer Iqbal, Doody's Book Reviews, March, 2014)

Erscheint lt. Verlag 10.9.2013
Zusatzinfo XI, 185 p.
Verlagsort Basel
Sprache englisch
Maße 155 x 235 mm
Gewicht 467 g
Themenwelt Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Schlagworte Cancer • Cardiovascular Diseases • immune response • NOD-like receptors • Pathogen-associated patterns • receptors • Toll-like receptors
ISBN-10 3-0348-0687-6 / 3034806876
ISBN-13 978-3-0348-0687-9 / 9783034806879
Zustand Neuware
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