Stem Cell and Gene Therapy for Cardiovascular Disease -

Stem Cell and Gene Therapy for Cardiovascular Disease (eBook)

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2015 | 1. Auflage
538 Seiten
Elsevier Science (Verlag)
978-0-12-801863-7 (ISBN)
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Stem Cell and Gene Therapy for Cardiovascular Disease is a state-of-the-art reference that combines, in one place, the breadth and depth of information available on the topic.

As stem cell and gene therapies are the most cutting-edge therapies currently available for patients with heart failure, each section of the book provides information on medical trials from contributors and specialists from around the world, including not only what has been completed, but also what is planned for future research and trials.

Cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals will find this book an invaluable resource for further study on the topic.


  • Provides information on stem and gene therapy medical trials from contributors and specialists around the world, including not only what has been completed, but also what is planned for future research and trials
  • Presents topics that can be applied to allogeneic cells, mesenchymal cells, gene therapy, cardiomyoctyes, iPS cells, MAPC's, and organogenesis
  • Covers the three areas with the greatest clinical trials to date: chronic limb ischemia, chronic angina, and acute MI
  • Covers the prevailing opinions on how to harness the body's natural repair mechanisms
  • Ideal resource for cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals

Stem Cell and Gene Therapy for Cardiovascular Disease is a state-of-the-art reference that combines, in one place, the breadth and depth of information available on the topic. As stem cell and gene therapies are the most cutting-edge therapies currently available for patients with heart failure, each section of the book provides information on medical trials from contributors and specialists from around the world, including not only what has been completed, but also what is planned for future research and trials. Cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals will find this book an invaluable resource for further study on the topic. Provides information on stem and gene therapy medical trials from contributors and specialists around the world, including not only what has been completed, but also what is planned for future research and trials Presents topics that can be applied to allogeneic cells, mesenchymal cells, gene therapy, cardiomyoctyes, iPS cells, MAPC's, and organogenesis Covers the three areas with the greatest clinical trials to date: chronic limb ischemia, chronic angina, and acute MI Covers the prevailing opinions on how to harness the body's natural repair mechanisms Ideal resource for cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals

List of Contributors


Deborah D. Ascheim

International Center for Health Outcomes & Innovation Research (InCHOIR), Department of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai; New York, NY, USA

Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Wayne Balkan,     Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL, USA

Akshay Bareja,     Mandel Center for Hypertension Research and Duke Cardiovascular Research Center, Department of Medicine, Duke University Medical Center, Durham, USA

Courtney E. Bartlett,     Division of Cardio-Thoracic Surgery, Department of Surgery, University of Utah, Salt Lake City, UT, USA

Atta Behfar,     Center for Regenerative Medicine, Mayo Clinic, Rochester, MN, USA

Lisle Blackbourn,     Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA

Roberto Bolli,     Institute of Molecular Cardiology, Division of Cardiovascular Medicine, Department of Medicine, University of Louisville, Louisville, KY, USA

L. Maximilian Buja

Cardiovascular Pathology Research Department, Texas Heart Institute, Houston, TX, USA

Department of Pathology and Laboratory Medicine, the University of Texas Health Science Center at Houston, TX, USA

Angela Castellanos,     Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL, USA

Antoine H. Chaanine,     Cardiovascular Research Center, Mount Sinai School of Medicine, New York, NY, USA

Eric Chau,     Texas Heart Institute, Department of Regenerative Medicine Research, Houston, TX, USA

Zhen Chen,     Department of Medicine, UC San Diego, San Diego, CA, USA

Karen L. Christman

Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA

Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA

Amy Chung,     NeoStem, Inc., New York, NY, USA

Robert M. Cole,     Cedars-Sinai Heart Institute, Los Angeles, CA, USA

John P. Cooke,     Houston Methodist Research Institute, Houston, TX, USA

H.J. Duckers,     Department of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands

Victor J. Dzau,     Mandel Center for Hypertension Research and Duke Cardiovascular Research Center, Department of Medicine, Duke University Medical Center, Durham, USA

Ray F. Ebert,     National Institutes of Health/National Heart, Lung, and Blood Institute, Bethesda, MD, USA

Jun Fujita,     Department of Cardiology, Keio University School of Medicine, Tokyo, Japan

Keiichi Fukuda,     Department of Cardiology, Keio University School of Medicine, Tokyo, Japan

Roberto Gaetani

Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA

Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA

Amir Gahremanpour,     Stem Cell Center and Adult Cardiology, Texas Heart Institute, Houston, TX, USA

W. Gathier,     Department of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands

Annetine C. Gelijns,     International Center for Health Outcomes & Innovation Research (InCHOIR), Department of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai; New York, NY, USA

Andrea S. Gobin,     Texas Heart Institute, Department of Regenerative Medicine Research, Houston, TX, USA

José A. Gomez,     Mandel Center for Hypertension Research and Duke Cardiovascular Research Center, Department of Medicine, Duke University Medical Center, Durham, USA

Roger J. Hajjar,     Cardiovascular Research Center, Mount Sinai School of Medicine, New York, NY, USA

Joshua M. Hare,     Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL, USA

Nirmala Hariharan,     Department of Pharmacology, University of California Davis, Davis, CA, USA

Timothy D. Henry,     Cedars-Sinai Heart Institute, Los Angeles, CA, USA

William Hiesinger,     Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA

Alan T. Hirsch,     University of Minnesota Medical School, Minneapolis, MN, USA

Conrad P. Hodgkinson,     Mandel Center for Hypertension Research and Duke Cardiovascular Research Center, Department of Medicine, Duke University Medical Center, Durham, USA

Kimberly N. Hong,     Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Kyung U. Hong,     Institute of Molecular Cardiology, Division of Cardiovascular Medicine, Department of Medicine, University of Louisville, Louisville, KY, USA

Thomas E. Ichim,     Institute for Molecular Medicine, Huntington Beach, CA, USA

E. Marc Jolicoeur,     Montreal Heart Institute, Université de Montréal, Montréal, Québec, Canada

Kazuki Kodo

Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA

Department of Medicine, Division of Cardiology, Stanford University, Stanford, CA, USA

Sandeep K. Krishnan,     Cedars-Sinai Heart Institute, Los Angeles, CA, USA

Michael J.B. Kutryk,     Interventional Cardiology Research, St. Michael’s Hospital; Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

David S. Lee,     Department of Medicine, University of California San Francisco, San Francisco, CA

Randall J. Lee

Department of Medicine, University of California San Francisco, San Francisco, CA

Cardiovascular Research Center, University of California San Francisco, San Francisco, CA

Institute for Regeneration Medicine, University of California San Francisco, San Francisco, CA

Division of Cardiology, Section of Cardiac Electrophysiology, University of California, San Francisco, CA

Douglas W. Losordo,     NeoStem, Inc., New York, NY, USA

Elton Migliati,     Texas Heart Institute, Houston, TX, USA

Leslie W. Miller,     Visiting Research and Clinical Consultant, Texas Heart Institute, Houston, TX, USA

Vivek Misra,     The University of Texas Health Science Center at San Antonio, Texas, USA

Lem Moyé,     University of Texas School of Public Health, Houston, TX, USA

Nathalie Nguyen,     Department of Biology, San Diego State University, San Diego, CA, USA

Sang-Ging Ong

Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA

Department of Medicine, Division of Cardiology, Stanford University, Stanford, CA, USA

Aaron Orozco,     Texas Heart Institute, Department of Regenerative Medicine Research, Houston, TX, USA

Amit N. Patel,     Division of Cardio-Thoracic Surgery, Department of Surgery, University of Utah, Salt...

Erscheint lt. Verlag 21.8.2015
Sprache englisch
Themenwelt Medizinische Fachgebiete Innere Medizin Kardiologie / Angiologie
Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Studium 2. Studienabschnitt (Klinik) Humangenetik
Naturwissenschaften Biologie Genetik / Molekularbiologie
ISBN-10 0-12-801863-1 / 0128018631
ISBN-13 978-0-12-801863-7 / 9780128018637
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