Nucleic Acid Aptamers
Humana Press Inc. (Verlag)
978-1-4939-3196-5 (ISBN)
Practical and easy to follow, Nucleic Acid Aptamers: Selection, Characterization, and Application provides a state-of-the-art summary of recent developments in the aptamer field and will be a helpful resource for scientists in the life sciences working with aptamers as tools to elucidate biological systems.
Selection of Aptamers for Metabolite Sensing and Construction of Optical Nanosensors.- SELEX of Cell-Specific RNA Aptamers.- Developing Aptamers by Cell-Based SELEX.- DNA Aptamer Generation by Genetic Alphabet Expansion SELEX (ExSELEX) Using an Unnatural Base Pair System.- Capillary Electrophoresis for the Selection of DNA Aptamers Recognizing Activated Protein C.- Preparation of SELEX Samples for Next-Generation Sequencing.- Next Generation Analysis of Deep Sequencing Data: Bringing Light into the Black Box of SELEX Experiments.- Aptamer Binding Studies Using MicroScale Thermophoresis.- Label-Free Determination of the Dissociation Constant of Small Molecule-Aptamer Interaction by Isothermal Titration Calorimetry.- Applications of Aptamers in Flow and Imaging Cytometry.- In Vitro and In Vivo Imaging of Fluorescent Aptamers.- Crystallographic Pursuit of a Protein-RNA Aptamer Complex.- Voltammetric Aptasensor Based on Magnetic Beads Assay for Detection of Human Activated Protein C.- Apta-PCR.- Aptamer-Based Enzyme-Capture-Assay for Measurement of Plasma Thrombin Levels.- Application of Aptamers in Histopathology.- Aptamer Stainings for Super-Resolution Microscopy.- Synthesis and Characterization of Aptamer Targeted SNALPs for the Delivery of siRNA.- Screening of Genetic Switches Based on the Twister Ribozyme Motif.
Erscheint lt. Verlag | 10.11.2015 |
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Reihe/Serie | Methods in Molecular Biology ; 1380 |
Zusatzinfo | 29 Illustrations, color; 20 Illustrations, black and white; XI, 242 p. 49 illus., 29 illus. in color. With online files/update. |
Verlagsort | Totowa, NJ |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
Schlagworte | Aptamer generation process • Aptamer-target interactions • Biophysical properties • Cell surfaces • Nucleic acids • Nukleinsäure • small molecules |
ISBN-10 | 1-4939-3196-2 / 1493931962 |
ISBN-13 | 978-1-4939-3196-5 / 9781493931965 |
Zustand | Neuware |
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