Stem Cell Biology in Neoplasms of the Central Nervous System (eBook)
XIII, 190 Seiten
Springer International Publishing (Verlag)
978-3-319-16537-0 (ISBN)
This volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used.
The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. Importantly, the realization that a distinct sub-population of cells contributes disproportionately to the growth and sustenance of central nervous system tumors has important implications for the treatment of such tumors. To treat CNS tumors, there is now a growing need to treat CSCs to achieve adequate tumor control.
Moneeb Ehtesham, M.D. is a Principal Investigator at the Department of Neurological Oncology at Vanderbilt University Medical Center. His research focuses on cellular therapies on malignant gliomas. He has published over 30 peer-reviewed publications, 3 book chapters, and 38 peer-reviewed abstracts/presentations. He has received over 1260 citations. Dr. Ehtesham has been awarded the Young Investigator Award (2003) by the American Association of Neurological Surgeons & Congress of Neurological Surgeons. He's also been listed in 'Who's Who in Stem Cell Research' by DataTrend Publications.
Imad Khan, M.D. is a Research Associate at the Geisel School of Medicine at Dartmouth College. His research focuses on therapies for neurosurgical diseases and disorders. He has published over 30 peer-reviewed publications, 3 book chapters, and over 40 peer-reviewed abstracts/presentations.
Moneeb Ehtesham, M.D. is a Principal Investigator at the Department of Neurological Oncology at Vanderbilt University Medical Center. His research focuses on cellular therapies on malignant gliomas. He has published over 30 peer-reviewed publications, 3 book chapters, and 38 peer-reviewed abstracts/presentations. He has received over 1260 citations. Dr. Ehtesham has been awarded the Young Investigator Award (2003) by the American Association of Neurological Surgeons & Congress of Neurological Surgeons. He's also been listed in "Who's Who in Stem Cell Research" by DataTrend Publications. Imad Khan, M.D. is a Research Associate at the Geisel School of Medicine at Dartmouth College. His research focuses on therapies for neurosurgical diseases and disorders. He has published over 30 peer-reviewed publications, 3 book chapters, and over 40 peer-reviewed abstracts/presentations.
1. Regulation of Subventricular Zone-Derived Cells Migration in the Adult Brain Vivian Capilla-Gonzalez, Emily Lavell, Alfredo Quiñones-Hinojosa, Hugo Guerrero-Cazares2. The SVZ and Its Relationship to Stem Cell Based Neuro-oncogenesisYael Kusne and Nader Sanai 3. Isolation and characterization of stem cells for human central nervous system malignanciesImad Saeed Khan and Moneeb Ehtesham4. The role of stem cells in pediatric central nervous system malignanciesBranavan Manoranjan, Neha Garg, David Bakhshinyan, Sheila K. Singh5. Laboratory models for central nervous system tumor stem cell researchImad Saeed Khan and Moneeb Ehtesham6. Radiation Therapy for Glioma Stem CellsAnthony E Rizzo, B.A. and Jennifer S. Yu7. Chemoresistance and chemotherapy targeting stem-like cells in malignant gliomaMia Dahl Sørensen, Sigurd Fosmark, Sofie Helwege, Dagmar Beier, Bjarne Winther Kristensen, Christoph Patrick Beier 8. Immunobiology and Immunotherapeutic targeting of glioma stem cells Mecca Madany, Tom M. Thomas, Lincoln Edwards, John S. Yu9. Emerging strategies for the treatment of tumor stem cells in central nervous system malignanciesImad Saeed Khan and Moneeb Ehtesham
| Erscheint lt. Verlag | 20.4.2015 |
|---|---|
| Reihe/Serie | Advances in Experimental Medicine and Biology | Advances in Experimental Medicine and Biology |
| Zusatzinfo | XIII, 190 p. 16 illus., 15 illus. in color. |
| Verlagsort | Cham |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Studium |
| Naturwissenschaften ► Biologie | |
| Technik | |
| Schlagworte | brain tumor • CSCs • Neuro-oncology • neuro stem cell research • tumor stem cells |
| ISBN-10 | 3-319-16537-2 / 3319165372 |
| ISBN-13 | 978-3-319-16537-0 / 9783319165370 |
| Haben Sie eine Frage zum Produkt? |
PDF (Wasserzeichen)Größe: 3,5 MB
DRM: Digitales Wasserzeichen
Dieses eBook enthält ein digitales Wasserzeichen und ist damit für Sie personalisiert. Bei einer missbräuchlichen Weitergabe des eBooks an Dritte ist eine Rückverfolgung an die Quelle möglich.
Dateiformat: PDF (Portable Document Format)
Mit einem festen Seitenlayout eignet sich die PDF besonders für Fachbücher mit Spalten, Tabellen und Abbildungen. Eine PDF kann auf fast allen Geräten angezeigt werden, ist aber für kleine Displays (Smartphone, eReader) nur eingeschränkt geeignet.
Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.
Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.
aus dem Bereich
