Molecular Basis of Autism (eBook)

S. Hossein Fatemi received his M.S. and Ph.D. degrees in human anatomy at University of Nebraska Medical Center in Omaha, Nebraska. Dr. Fatemi subsequently earned his M.D. from Case Western Reserve University School of Medicine. Since 1996, Dr. Fatemi has been a faculty member at the Department of Psychiatry at the University of Minnesota School of Medicine where he is currently a Professor of Psychiatry and Neuroscience and the Associate Chair for Neuroscience and Translational Research. He has studied the basis of neurodevelopmental disorders, primarily autism and schizophrenia for over eighteen years. He has also developed a mouse model of prenatal viral infection in studies of brain development, elucidated the role of the Reelin and GABAergic signaling systems in autism, schizophrenia and mood disorders, and investigated safe and effective means of treating nicotine addiction in subjects with schizophrenia. Dr. Fatemi is a Distinguished Fellow of the American Psychiatric Association, a Fellow of the American College of Neuropsychopharmacology and Collegium Internationale Neuropsychopharmacologicum, and serves as a member of several editorial boards.     

Section I. Clinical Aspects of Autism1. A Brief History of AutismFred R. Volkmar 2. Autism Spectrum Disorder: Diagnostic ConsiderationsGeorge M. Realmuto 3. Epidemiologic Features of Autism Spectrum DisordersRussell Kirby 4. Genetics of Autism Spectrum Disorders: The Opportunity and Challenge in the Genetics ClinicYi Wang, Ping Wang, Xiu Xu, Jennifer Goldstein, Sau W. Cheung, Yong-hui Jiang 5. Epigenetic Regulation in AutismCyril J. Peter, Abraham Reichenberg, Schahram Akbarian 6. Immunology of AutismDestanie R. Rose, Paul Ashwood 7. Neuroimaging in Autism Spectrum DisordersDanielle Baribeau, Evdokia Anagnostou 8. The Neuropathology of AutismManuel F. Casanova 9. Pharmacology of ASD Spectrum DisorderDonald E. Greydanus, Gabriel Kaplan, Dilip R. Patel 10. Behavioral TherapiesV. Mark Durand Section II. Basic Science Aspects of Autism11. Autism and DopamineGuy Mittleman, Charles D. Blaha 12. Autism and GlutamateMaria L. Carlsson 13. Serotonin in Autism Spectrum Disorder: Insights From Human Studies and Animal ModelsNatalia Benza, Diane C. Chugani 14. Oxytocin and Vasopressin in Autism and Genetic SyndromesTal Levin-Decanini, Sunday M. Francis, Angela Sagar, Wensheng Liu, C. Sue Carter, Suma Jacob 15. Molecular basis of cholinergic changes in autistic spectrum disorders and relevance for treatment interventions.Elizabeta B. Mukaetova-Ladinska, Elaine K. Perry 16. Reelin, GABA, FMRP, and AutismTimothy D. Folsom, S. Hossein Fatemi 17. The Role of Neurexins and Neuroligins in AutismAmy C. Reichelt, James Dachtler 18. Neurotrophins, their receptors and autism: ligand vs. receptor abnormalitiesElizabeth M. Sajdel-Sulkowska 19. Cognition, Motor Control and Other Aspects of Autism: A Pragmatic ReviewJames W. Howell, Detlef H. Heck 20. Increased vulnerability to oxidative stress and mitochondrial dysfunction in autismAbha Chauhan, Ved Chauhan