Stem Cells and Prostate Cancer -

Stem Cells and Prostate Cancer

Scott D. Cramer (Herausgeber)

Buch | Softcover
182 Seiten
2015 | 2013 ed.
Springer-Verlag New York Inc.
978-1-4939-0094-7 (ISBN)
169,98 inkl. MwSt
​​​​Recent evidence demonstrates that normal prostate tissue contains stem cells.  There is also accumulating evidence that prostate cancer contains a population of cells with stem cell-like characteristics referred to as cancer stem cells, or tumor initiating cells.  Both the normal prostate stem cell and cancer stem cell populations have important implications for the generation, therapeutic targeting, and prevention of prostate cancer.  The purpose of this book is to explore the role of stem cells in prostate cancer, which is becoming an increasingly hot trend in cancer research. ​

Preface.- Stem Cells and Prostate Development.- Isolation and Characterization of Prostate Stem Cells.- Prostate tumor initiating cells.- TIC Markers and methods of characterization.- Genetic Control of Self Renewal of the TIC.- Therapeutic targeting of the prostate TIC.- The prostate stem cell niche.- Tumor stroma control of the prostate TIC.- Targeting the prostate stem cell for chemoprevention.- Stem cell models for functional validation of prostate cancer genes.- Index​.

Erscheint lt. Verlag 8.2.2015
Zusatzinfo VII, 182 p.
Verlagsort New York
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Medizin / Pharmazie Studium
Naturwissenschaften Biologie Zellbiologie
Schlagworte androgen receptors • MicroRNAs • p57 • Tumor-initiating cells • tumor suppressors
ISBN-10 1-4939-0094-3 / 1493900943
ISBN-13 978-1-4939-0094-7 / 9781493900947
Zustand Neuware
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