Stem Cells and Prostate Cancer

Scott D. Cramer (Herausgeber)

Buch | Hardcover

182 Seiten

2013 | 2013 ed.
Springer-Verlag New York Inc.
978-1-4614-6497-6 (ISBN)

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Recent evidence demonstrates that normal prostate tissue contains stem cells. There is also accumulating evidence that prostate cancer contains a population of cells with stem cell-like characteristics referred to as cancer stem cells, or tumor initiating cells. Both the normal prostate stem cell and cancer stem cell populations have important implications for the generation, therapeutic targeting, and prevention of prostate cancer. The purpose of this book is to explore the role of stem cells in prostate cancer, which is becoming an increasingly hot trend in cancer research.

Please see attached CV for details. The volume editor has received millions of dollars in grants from the NIH and NCI for projects on prostate cancer stem cells.

Preface.- Stem Cells and Prostate Development.- Isolation and Characterization of Prostate Stem Cells.- Prostate tumor initiating cells.- TIC Markers and methods of characterization.- Genetic Control of Self Renewal of the TIC.- Therapeutic targeting of the prostate TIC.- The prostate stem cell niche.- Tumor stroma control of the prostate TIC.- Targeting the prostate stem cell for chemoprevention.- Stem cell models for functional validation of prostate cancer genes.- Index.

Zusatzinfo	VII, 182 p.
Verlagsort	New York, NY
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Medizin / Pharmazie ► Studium
	Naturwissenschaften ► Biologie ► Zellbiologie
ISBN-10	1-4614-6497-8 / 1461464978
ISBN-13	978-1-4614-6497-6 / 9781461464976
Zustand	Neuware